38076-73-2Relevant articles and documents
Utilizing d–pπ Bonds for Ultralong Organic Phosphorescence
Tian, Shuai,Ma, Huili,Wang, Xuan,Lv, Anqi,Shi, Huifang,Geng, Yun,Li, Jie,Liang, Fushun,Su, Zhong-Min,An, Zhongfu,Huang, Wei
supporting information, p. 6645 - 6649 (2019/04/04)
Developing pure organic materials with ultralong lifetimes is attractive but challenging. Here we report a concise chemical approach to regulate the electronic configuration for phosphorescence enhancement. After the introduction of d–pπ bonds into a phenothiazine model system, a phosphorescence lifetime enhancement of up to 19 times was observed for DOPPMO, compared to the reference PPMO. A record phosphorescence lifetime of up to 876 ms was obtained in phosphorescent phenothiazine. Theoretical calculations and single-crystal analysis reveal that the d–pπ bond not only reduces the (n, π*) proportion of the T1 state, but also endows the rigid molecular environment with multiple intermolecular interactions, thus enabling long-lived phosphorescence. This finding makes a valuable contribution to the prolongation of phosphorescence lifetimes and the extension of the scope of phosphorescent materials.
Synthesis and bio-evaluation of phenothiazine derivatives as new anti-tuberculosis agents
He, Chun-Xian,Meng, Hui,Zhang, Xiang,Cui, Hua-Qing,Yin, Da-Li
supporting information, p. 951 - 954 (2015/08/18)
Abstract Two series of phenothiazine derivatives were designed and synthesized. All compounds were tested for anti-tuberculosis activities against Mycobacterium tuberculosis H37RV. In comparison with mother compound of chlorpromazine, compound 6e shows promising anti-tuberculosis activity and much less mammalian cell cytotoxicity, compound 6e merits to be further explored as new anti-tuberculosis agents.
N-benzoylated phenoxazines and phenothiazines: Synthesis, antiproliferative activity, and inhibition of tubulin polymerization
Prinz, Helge,Chamasmani, Behfar,Vogel, Kirsten,B?hm, Konrad J.,Aicher, Babette,Gerlach, Matthias,Günther, Eckhard G.,Amon, Peter,Ivanov, Igor,Müller, Klaus
supporting information; experimental part, p. 4247 - 4263 (2011/08/05)
A total of 53 N-benzoylated phenoxazines and phenothiazines, including their S-oxidized analogues, were synthesized and evaluated for antiproliferative activity, interaction with tubulin, and cell cycle effects. Potent inhibitors of multiple cancer cell l
