38090-53-8 Usage
Description
TRANS-4-AMINOCROTONIC ACID, also known as TACA, is an organic compound that functions as a GABAA and GABAC agonist or antagonist. It has potential applications in the treatment of vascular diseases and is also utilized in research for cancer vaccines and carbohydrate epitopes.
Uses
Used in Pharmaceutical Industry:
TRANS-4-AMINOCROTONIC ACID is used as a GABAA and GABAC agonist or antagonist for the treatment of vascular diseases, targeting the GABA receptors to regulate blood flow and pressure.
Used in Cancer Research:
In the field of cancer research, TRANS-4-AMINOCROTONIC ACID is used in the development of cancer vaccines, potentially enhancing the immune response against cancer cells and contributing to the prevention or treatment of various types of cancer.
Used in Carbohydrate Epitope Studies:
TRANS-4-AMINOCROTONIC ACID is also utilized in the study of carbohydrate epitopes, which are important for understanding the molecular recognition and interactions between cells and pathogens. This research can lead to the development of new diagnostic tools and therapeutic strategies for various diseases.
Biological Activity
The trans-isomer of CACA. Potent GABA A agonist, GABA uptake inhibitor and substrate for GABA-T. Also GABA C agonist.
Check Digit Verification of cas no
The CAS Registry Mumber 38090-53-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,0,9 and 0 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 38090-53:
(7*3)+(6*8)+(5*0)+(4*9)+(3*0)+(2*5)+(1*3)=118
118 % 10 = 8
So 38090-53-8 is a valid CAS Registry Number.
InChI:InChI=1/C4H7NO2/c5-3-1-2-4(6)7/h1-2H,3,5H2,(H,6,7)/b2-1+
38090-53-8Relevant articles and documents
Synthesis of gamma aminocrotonic acid and of gamma amino butyric acid.
MUSASHI
, p. 71 - 73 (1954)
-
INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHODS OF THEIR USE
-
Page/Page column 149, (2018/06/30)
Compounds of formula (I') and methods of their use and preparation, as well as compositions comprising compounds of formula (I').
INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHODS OF THEIR USE
-
Page/Page column 149, (2017/09/02)
The present disclosure is directed to compounds of formula I and methods of their use and preparation, as well as compositions comprising compounds of formula I.
