38113-96-1

Basic information

• Product Name: methyl (Z)-2-(hydroxyimino)-2-phenylacetate
• Synonyms: methyl (Z)-2-(hydroxyimino)-2-phenylacetate
• CAS NO: 38113-96-1
• Molecular Weight: 179.175
• Mol File: 38113-96-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl (Z)-2-(hydroxyimino)-2-phenylacetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (Z)-2-(hydroxyimino)-2-phenylacetate(38113-96-1)
• EPA Substance Registry System: methyl (Z)-2-(hydroxyimino)-2-phenylacetate(38113-96-1)

Safety Data

• Hazardous Substances Data: 38113-96-1(Hazardous Substances Data)

Upstream product

• 25327-36-0 (Z)-2-(hydroxyimino)-2-phenylacetic acid 
• 15206-55-0 methyl 2-oxo-2-phenylacetate 

Downstream Products

• 105394-78-3 2-(N,N-diethylamino)-2-phenylacetic acid methyl ester 
• 1408233-57-7 C₁₆H₁₅NO₅S 
• 1408233-58-8 C₁₅H₂₃NO₃Si 
• 39684-39-4 (Z)-methyl 2-(methoxyimino)-2-phenylacetate 

Relevant articles and documents

Double nucleophilic N-alkylation of α-oxime-esters with Grignard reagents

Double nucleophilic N-alkylation of α-oxime-esters, affording N,N-dialkyl-α-amino acids is herein described. Grignard reagents accomplished double N-alkylations via umpolung and various N,N-dialkylated α-amino acids were successfully synthesized in 15 min. Both electron-withdrawing sulfonyl groups and electron-donating silyl and methyl groups on oximes were available. Alkylmagnesium species and (E)-configuration of α-oxime-ester were essential to this cascade reaction.