38160-59-7Relevant articles and documents
A mild and chemoselective CALB biocatalysed synthesis of sulfoxides exploiting the dual role of AcOEt as solvent and reagent
Anselmi, Silvia,Liu, Siyu,Kim, Seong-Heun,Barry, Sarah M.,Moody, Thomas S.,Castagnolo, Daniele
supporting information, p. 156 - 161 (2021/01/14)
A mild, chemoselective and sustainable biocatalysed synthesis of sulfoxides has been developed exploiting CALB and using AcOEt with a dual role of more environmentally friendly reaction solvent and enzyme substrate. A series of sulfoxides, including the drug omeprazole, have been synthesised in high yields and with excellent E-factors.
Thioboration of α,β-unsaturated ketones and aldehydes toward the synthesis of β-sulfido carbonyl compounds
Civit, Marc G.,Sanz, Xavier,Vogels, Christopher M.,Webb, Jonathan D.,Geier, Stephen J.,Decken, Andreas,Bo, Carles,Westcott, Stephen A.,Fernández, Elena
supporting information, p. 2148 - 2154 (2015/05/19)
Herein a direct β-sulfido carbonyl compound synthesis by the easy activation of RS-Bpin reagents with α,β-unsaturated ketones and aldehydes is reported. This convenient methodology can be performed at room temperature with no other additives. The key poin
Supported cobalt complex-catalysed conjugate addition of indoles, amines and thiols to α,β-unsaturated compounds
Rajabi, Fatemeh,Razavi, Sepideh,Luque, Rafael
experimental part, p. 786 - 789 (2010/09/05)
A highly active and reusable supported Co(ii) complex on SBA-15 shows an excellent activity and selectivity to target products in aza- and thia-Michael conjugate additions of indoles, amines and thiols to α,β-unsaturated compounds under solventless mild reaction conditions. The Co-catalyst was also highly reusable and comparably more active than related catalysts in the reaction.
