381670-28-6 Usage
Description
N-ETHOXYCARBONYL-3-NITRO-O-TOLUIDINE, also known as ethyl 3-nitro-2-methylaniline-4-carboxylate, is an organic compound characterized by its molecular formula C11H12N2O4 and a molar mass of 232.22 g/mol. This versatile chemical intermediate features a nitro group, a methyl group, and an ethoxycarbonyl group within its structure, making it a valuable building block for the synthesis of a variety of organic molecules.
Uses
Used in Pharmaceutical Industry:
N-ETHOXYCARBONYL-3-NITRO-O-TOLUIDINE is used as a chemical intermediate for the synthesis of pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Organic Dyes Industry:
In the realm of organic dyes, N-ETHOXYCARBONYL-3-NITRO-O-TOLUIDINE serves as an intermediate, playing a crucial role in the production of various dye compounds. Its presence in these dyes can influence their color, stability, and application potential.
Used in Organic Synthesis:
N-ETHOXYCARBONYL-3-NITRO-O-TOLUIDINE is utilized in organic synthesis for the creation of diverse organic molecules. Its functional groups enable it to participate in numerous chemical reactions, facilitating the synthesis of complex organic compounds.
Used in Research:
N-ETHOXYCARBONYL-3-NITRO-O-TOLUIDINE is also employed in research settings, where it can be used to study various chemical reactions and explore new methods of synthesis. Its presence in experiments can provide insights into the reactivity and behavior of similar compounds.
Used in Manufacturing Processes:
N-ETHOXYCARBONYL-3-NITRO-O-TOLUIDINE is integrated into manufacturing processes, particularly those related to the production of pharmaceuticals and dyes. Its role in these processes is essential for the efficient and effective creation of end products.
It is important to handle and store N-ETHOXYCARBONYL-3-NITRO-O-TOLUIDINE according to standard laboratory safety protocols to ensure the safety of individuals and the integrity of the compound.
Check Digit Verification of cas no
The CAS Registry Mumber 381670-28-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,8,1,6,7 and 0 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 381670-28:
(8*3)+(7*8)+(6*1)+(5*6)+(4*7)+(3*0)+(2*2)+(1*8)=156
156 % 10 = 6
So 381670-28-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H12N2O4/c1-3-16-10(13)11-8-5-4-6-9(7(8)2)12(14)15/h4-6H,3H2,1-2H3,(H,11,13)
381670-28-6Relevant articles and documents
Synthesis and Biological Evaluation of New 1,2-Dihydro-4-hydroxy-2-oxo-3-quinolinecarboxamides for Treatment of Autoimmune Disorders: Structure-Activity Relationship
J?nsson, Stig,Andersson, Gunnar,Fex, Tomas,Fristedt, Tomas,Hedlund, Gunnar,Jansson, Karl,Abramo, Lisbeth,Fritzson, Ingela,Pekarski, Olga,Runstr?m, Anna,Sandin, Helena,Thuvesson, Ingela,Bj?rk, Anders
, p. 2075 - 2088 (2007/10/03)
Roquinimex-related 3-quinolinecarboxamide derivatives were prepared and evaluated for treatment of autoimmune disorders. The compounds were tested in mice for their inhibitory effects on disease development in the acute experimental autoimmune encephalomyelitis model and selected compounds in the beagle dog for induction of proinflammatory reaction. Structure-activity relationships are discussed. Compound 8c, laquinimod, showed improved potency and superior toxicological profile compared to the lead compound roquinimex (1b, Linomide) and was selected for clinical studies (currently in phase II).
