381723-16-6 Usage
Description
2-Ethynyl-1,3-difluoro-benzene, also known as 1,3-difluoro-2-ethynylbenzene, is an organic chemical compound characterized by the molecular formula C8H4F2 and a molar mass of 144.1 g/mol. This colorless liquid possesses a strong odor and is primarily utilized in the synthesis of agrochemicals and pharmaceuticals. Due to its highly flammable nature and potential to cause skin and eye irritation, it requires careful handling and adherence to safety protocols.
Uses
Used in Agrochemical Industry:
2-Ethynyl-1,3-difluoro-benzene serves as a key intermediate in the production of various agrochemicals, contributing to the development of effective pest control agents and crop protection products. Its unique chemical structure allows for the creation of compounds with specific pesticidal properties, enhancing agricultural productivity and crop quality.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 2-Ethynyl-1,3-difluoro-benzene is employed as a building block for the synthesis of diverse medicinal compounds. Its distinctive molecular structure facilitates the design of innovative drugs with targeted therapeutic effects, addressing a wide range of health conditions and contributing to advancements in medical treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 381723-16-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,8,1,7,2 and 3 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 381723-16:
(8*3)+(7*8)+(6*1)+(5*7)+(4*2)+(3*3)+(2*1)+(1*6)=146
146 % 10 = 6
So 381723-16-6 is a valid CAS Registry Number.
381723-16-6Relevant articles and documents
New bicyclic compounds as crac channel modulators
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Paragraph 0113; 0135, (2014/06/24)
The present invention relates to novel compounds which are inhibitors of CRAC channel activity. This invention also relates to pharmaceutical compositions containing them, process for their preparation and their use in therapy.
General and selective head-to-head dimerization of terminal alkynes proceeding via hydropalladation pathway
Jahier, Claire,Zatolochnaya, Olga V.,Zvyagintsev, Nickolay V.,Ananikov, Valentine P.,Gevorgyan, Vladimir
, p. 2846 - 2849 (2012/07/17)
A general highly regio- and stereoselective palladium-catalyzed head-to-head dimerization reaction of terminal acetylenes is presented. This methodology allows for the efficient synthesis of a variety of 1,4-enynes as single E stereoisomers. Computational studies reveal that this dimerization reaction proceeds via the hydropalladation pathway.
