382-19-4

Basic information

• Product Name: Propanoyl chloride, 3,3,3-trifluoro-2-(trifluoromethyl)-
• CAS NO: 382-19-4
• Molecular Formula: C4HClF6O
• Mol File: 382-19-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Propanoyl chloride, 3,3,3-trifluoro-2-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoyl chloride, 3,3,3-trifluoro-2-(trifluoromethyl)-(382-19-4)
• EPA Substance Registry System: Propanoyl chloride, 3,3,3-trifluoro-2-(trifluoromethyl)-(382-19-4)

Safety Data

• Hazardous Substances Data: 382-19-4(Hazardous Substances Data)

Upstream product

• 4074-09-3 α-hydrohexafluoroisobutyric aldehyde 
• 360-58-7 1-ethoxy-1,3,3,3-tetrafluoro-2-trifluoromethyl-propene 
• 564-10-3 3,3,3-trifluoro-2-(trifluoromethyl)propanoic acid 
• 684-22-0 bis(trifluoromethyl)ketene 
• 382-22-9 3,3,3-trifluoro-2-trifluoromethyl-propionyl fluoride 

Downstream Products

• 564-10-3 3,3,3-trifluoro-2-(trifluoromethyl)propanoic acid 
• 51253-93-1 N-Cyclohexyl-4,4,4-trifluoro-2-oxo-3-trifluoromethyl-butyrimidoyl chloride 
• 786-39-0 β,β,β,β',β',β'-hexafluoro-isobutyric acid anilide 

Relevant articles and documents

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Synthesis of 1-aroyl(1-arylsulfonyl)-4-bis(trifluoromethyl)alkyl semicarbazides as potential physiologically active compounds

1,1-Bis(trifluoromethyl)alkyl isocyanates obtained from perfluoroisobutene (PFIB) react with aroyl(arylsulfonyl)hydrazines. Twenty eight prospective biologically active polyfluorinated 1,4-substituted semicarbazides were synthesized. The structure of each

Synthesis and anticancer activity of N-bis(trifluoromethyl)alkyl-N′-thiazolyl and N-bis(trifluoromethyl)alkyl-N′-benzothiazolyl ureas

A number of N-bis(trifluoromethyl)alkyl-N′-thiazolyl and -benzothiazolyl ureas have been synthesized and evaluated for their in vitro antiproliferative activities against the human cancer cell lines at the National Cancer Institute (NCI, USA). The activity was shown for compounds 8a,c and 9a-c. The most sensitive cell lines relative to the tested compounds are: 8c PC-3 (prostate cancer, log GI50 -7.10), 9c SNB-75 (CNS cancer, log GI50 -5.84), 9b UO-31 (renal cancer, log GI50 -5.66), and SR (leukemia, log GI50 -5.44) human cancer cells.