382-66-1 Usage
Description
9-fluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-methanesulphonate, also known as (11β)-9-Fluoro-11,17-dihydroxy-21-[(methylsulfonyl)oxy]pregna-1,4-diene-3,20-dione, is a chemical compound derived from the pregnane class of steroid hormones. It is characterized by its unique molecular structure, which includes a fluorine atom at the 9th position, hydroxyl groups at the 11th and 17th positions, and a methanesulfonyl group at the 21st position. 9-fluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-methanesulphonate serves as an intermediate in the synthesis of other pharmaceutically relevant molecules.
Uses
Used in Pharmaceutical Industry:
9-fluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-methanesulphonate is used as an intermediate in the synthesis of Desmethyl Fluorometholone (D291980) for its glucocorticoid properties. It is particularly effective in treating ocular inflammation due to its potent anti-inflammatory and immunosuppressive actions.
Used in Ophthalmology:
In the field of ophthalmology, 9-fluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-methanesulphonate is used as a precursor for the synthesis of Fluorometholone (F593145), a glucocorticoid steroid that is applied topically to manage various eye conditions, such as uveitis, iritis, and postoperative inflammation following ocular surgery.
Used in Quality Control and Impurity Profiling:
As an impurity in the synthesis of Fluorometholone, 9-fluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-methanesulphonate is also utilized in quality control processes to ensure the purity and safety of the final pharmaceutical product. This helps in maintaining the efficacy and minimizing potential side effects associated with the use of the drug.
Check Digit Verification of cas no
The CAS Registry Mumber 382-66-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,8 and 2 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 382-66:
(5*3)+(4*8)+(3*2)+(2*6)+(1*6)=71
71 % 10 = 1
So 382-66-1 is a valid CAS Registry Number.
