38201-64-8

Basic information

• Product Name: 2-MERCAPTO-5,6-DIMETHYLTHIENO[2,3-D]PYRIMIDIN-4(3H)-ONE
• Synonyms: 5,6-dimethyl-2-sulfanylidene-1H,2H,3H,4H-thieno[2,3-d]pyrimidin-4-one
• CAS NO: 38201-64-8
• Molecular Formula: C₈H₈N₂OS₂
• Molecular Weight: 0
• Mol File: 38201-64-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.47g/cm³
• Refractive Index: 1.706
• CAS DataBase Reference: 2-MERCAPTO-5,6-DIMETHYLTHIENO[2,3-D]PYRIMIDIN-4(3H)-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-MERCAPTO-5,6-DIMETHYLTHIENO[2,3-D]PYRIMIDIN-4(3H)-ONE(38201-64-8)
• EPA Substance Registry System: 2-MERCAPTO-5,6-DIMETHYLTHIENO[2,3-D]PYRIMIDIN-4(3H)-ONE(38201-64-8)

Safety Data

• Hazardous Substances Data: 38201-64-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H8N2OS2/c1-3-4(2)13-7-5(3)6(11)9-8(12)10-7/h1-2H3,(H2,9,10,11,12)

Upstream product

• 132424-47-6 5,6-Dimethyl-4-m-tolylamino-1H-thieno[2,3-d]pyrimidine-2-thione 
• 132424-46-5 5,6-Dimethyl-4-p-tolylamino-1H-thieno[2,3-d]pyrimidine-2-thione 
• 132424-45-4 5,6-Dimethyl-4-phenylamino-1H-thieno[2,3-d]pyrimidine-2-thione 
• 132424-48-7 4-(4-Chloro-phenylamino)-5,6-dimethyl-1H-thieno[2,3-d]pyrimidine-2-thione 
• 132424-49-8 4-(4-Methoxy-phenylamino)-5,6-dimethyl-1H-thieno[2,3-d]pyrimidine-2-thione 
• 333-20-0 potassium thioacyanate 
• 4815-24-1 2-amino-4,5-dimethyl-3-thiophenecarboxylic acid ethyl ester 
• 1147550-11-5 ammonium thiocyanate 
• 4651-94-9 2-amino-4,5-dimethylthiophene-3-carbonitrile 
• 126105-81-5 3-(4-Chloro-phenyl)-4-imino-5,6-dimethyl-3,4-dihydro-1H-thieno[2,3-d]pyrimidine-2-thione 
• 126105-82-6 4-Imino-3-(4-methoxy-phenyl)-5,6-dimethyl-3,4-dihydro-1H-thieno[2,3-d]pyrimidine-2-thione 
• 126105-79-1 4-Imino-5,6-dimethyl-3-phenyl-3,4-dihydro-1H-thieno[2,3-d]pyrimidine-2-thione 
• 126105-80-4 4-Imino-5,6-dimethyl-3-p-tolyl-3,4-dihydro-1H-thieno[2,3-d]pyrimidine-2-thione 
• 132424-59-0 1-(3-Cyano-4,5-dimethyl-thiophen-2-yl)-3-phenyl-thiourea 

Downstream Products

• 42518-50-3 2-(ethylthio)-5,6-dimethyl-3H,4H-thieno[2,3-d]pyrimidin-4-one 
• 54968-60-4 (6,7-dimethyl-1-oxo-1,2-dihydrothieno[2,3-d]pyrimidin-3-ylsulfanyl)acetic acid 
• 52881-19-3 5,6-dimethyl-2-(2-oxo-2-phenyl-ethylsulfanyl)-3H-thieno[2,3-d]pyrimidin-4-one 
• 276255-32-4 2,3-dihydro-6,7-dimethyl-2-(phenylmethylene)-5H-thiazolo[3,2-a]thieno[2,3-d]pyrimidine-3,5-dione 
• 146381-74-0 (6,7-dimethyl-1-oxo-1,2-dihydrothieno[2,3-d]pyrimidin-3-ylsulfanyl)acetic acid ethyl ester 
• 53074-16-1 5,6-dimethyl-2-methylthio-3,4-dihydrothieno[2,3-d]pyrimidin-4-one 

Relevant articles and documents

Oxidative cyclocondensation of cyclic thio-and selenoureas. 5. 2-Thioxothieno-and 2-thioxopyrido[2,3-d]pyrimidin-4-ones

A study was carried out on the oxidative cyclocondensation of 2-thioxothieno-and 2-thioxopyrido[2,3-d]pyrimidin-4-ones. The thiophene ring with excess π-electron density facilitates the reaction, while the pyridine ring with diminished π-electron density hinders it. 2-Thioxothieno-[2,3-d] pyridimin-4-ones were converted into previously unreported 7H,13H-[1,2,4] thiadiazolo-[3,2-b:5,4-b′]bis(thieno[2,3-d]pyridimine-7,13-diones).

Investigation into the reaction of 2-amino- 4,5-dimethylthiophene-3- carboxamide with iso(and Isothio)cyanates under microwave irradiation

The reaction of 2-amino-4,5-dimethyl-thiophene-3-carboxamide with iso(and isothio) cyanates for the synthesis ofthieno[2,3-d]pyrimidines has been investigated. The reactions under microwave irradiation in the presence of N,N-dimethyl acetamide as solvent

MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH

The present invention provides screening methods for identifying modifiers of chemosensory receptors and their ligands, e.g., by determining whether a test entity is suitable to interact with one or more interacting sites within the Venus flytrap domains of the chemosensory receptors as well as modifiers capable of modulating chemosensory receptors and their ligands.