38210-45-6

Basic information

• Product Name: 2-(benzo[b]thiophen-2-yl)benzenamine
• Synonyms: 2-(benzo[b]thiophen-2-yl)benzenamine
• CAS NO: 38210-45-6
• Molecular Weight: 225.314
• Mol File: 38210-45-6.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 2-(benzo[b]thiophen-2-yl)benzenamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(benzo[b]thiophen-2-yl)benzenamine(38210-45-6)
• EPA Substance Registry System: 2-(benzo[b]thiophen-2-yl)benzenamine(38210-45-6)

Safety Data

• Hazardous Substances Data: 38210-45-6(Hazardous Substances Data)

Upstream product

• 758640-21-0 N-Benzylaniline 
• 612-98-6 N-benzyl-N-phenylnitrous amide 
• 95-15-8 Benzo[b]thiophene 
• 98437-23-1 benzo[b]thiophene-2-boronic acid 
• 615-43-0 2-iodophenylamine 
• 615-36-1 2-bromoaniline 
• 577-19-5 2-nitrophenyl bromide 

Downstream Products

• 1609211-27-9 C₂₀H₁₄N₂OS 
• 1207-95-0 2-phenylbenzo[b]thiophene 
• 1367458-53-4 6-phenylbenzo[b]naphtho[2,1-d]thiophene 
• 239-35-0 11-thiabenzo[a]fluorene 

Relevant articles and documents

Fluorescent chemosensor for Al(III) based on chelation-induced fluorescence enhancement and its application in live cells imaging

A tridentate Schiff base receptor BPB was synthesized by condensation of 2-(benzo[b]thiophen-2-yl)benzenamine with salicylaldehyde in ethanolic medium and characterized by various spectral (FT-IR, 1H NMR, 13C NMR and mass) data. The methanolic solution of BPB was applied for the fluorescent sensing of metal ions dissolved in aqueous medium. The selectivity experiment revealed that the receptor BPB showed significant fluorescence enhancement at 430 nm in the presence of A(III) due to the chelation-induced fluorescence enhancement (CHEF) mechanism. Receptor BPB formed complex with Al(III) in 2:1 binding ratio with the estimated binding constant of K = 3.02 × 108 M?2. Without any interference from other tested metal ions, the receptor BPB can detect the concentration of Al(III) down to 256 nM. The receptor BPB showed good cell permeability and was applied for the qualitative and quantitative detection of intracellular Al(III) in A549 cell line (adenocarcinomic human alveolar basal epithelial cells) by using a confocal imaging technique.

Direct photoexcitation of benzothiazolines: Acyl radical generation and application to access heterocycles

An acyl radical generation and functionalization strategy through direct photoexcitation of benzothiazolines has been developed. The formed acyl radical species can either be trapped by quinoxalin-2-ones to realize their C(3)-H functionalization or trigger a cascade radical cyclization with isonitriles to synthesise biologically important phenanthridines. The synthetic value of this protocol can be further illustrated by the modification of quinoxalin-2-ones, containing important natural products and drug-based complex molecules.

Photochemical intramolecular amination for the synthesis of heterocycles

Polycyclic heterocycles can be formed in good to excellent yields via photochemical conversion of the corresponding substituted aryl azides under irradiation with purple LEDs in a continuous flow reactor. The experimental set-up is tolerant to UV-sensitive functional groups while affording diverse carbazoles, as well as an indole and pyrrole framework, in short reaction times. The photochemical method is presumed to progress through a mechanism differing from the other methods of azide activation involving transition metal catalysis.