38212-14-5

Basic information

• Product Name: α-Isobutylstyrene
• Synonyms: (3-Methyl-1-methylenebutyl)benzene;4-Methyl-2-phenyl-1-pentene;α-Isobutylstyrene
• CAS NO: 38212-14-5
• Molecular Formula: C₁₂H₁₆
• Molecular Weight: 0
• Mol File: 38212-14-5.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: α-Isobutylstyrene(CAS DataBase Reference)
• NIST Chemistry Reference: α-Isobutylstyrene(38212-14-5)
• EPA Substance Registry System: α-Isobutylstyrene(38212-14-5)

Safety Data

• Hazardous Substances Data: 38212-14-5(Hazardous Substances Data)

Upstream product

• 109-72-8 n-butyllithium 
• 582-62-7 3-methyl-1-phenylbutan-1-one 
• 2065-66-9 methyl-triphenylphosphonium iodide 
• 4423-54-5 (+/-)-4-methyl-2-phenylpentan-2-ol 
• 1116-39-8 triisobutylborane 
• 76886-55-0 Acetophenone 2,4,6-triisopropylbenzenesulphonyl hydrazone 
• 108-86-1 bromobenzene 
• 126344-10-3 Diisobutyl-(3-methyl-1-methylene-butyl)-borane 
• 4113-63-7 1-chloro-4-methylpentan-2-one 
• 140226-88-6 Dithiocarbonic acid S-methyl ester S-((Z)-4-methyl-2-phenyl-pent-2-enyl) ester 
• 691-37-2 4-Methyl-1-pentene 
• 17763-67-6 Phenyl triflate 
• 26190-67-0 toluene-4-sulfonic acid 1-phenylvinyl ester 
• 5674-02-2 2-methylpropylmagnesium chloride 

Downstream Products

• 19219-84-2 (1,3-dimethylbutyl)benzene 
• 112778-37-7 (3-Difluoromethylene-1-isobutyl-cyclobutyl)-benzene 
• 112778-30-0 (2,2-Difluoro-1-isobutyl-3-methylene-cyclobutyl)-benzene 
• 1186000-51-0 [(2S)-4-methylpentan-2-yl]benzene 
• 1228632-19-6 [(2R)-4-methylpentan-2-yl]benzene 
• 1325729-43-8 (R)-(+)-4,4,5,5-tetramethyl-2-(4-methyl-2-phenylpentyl)-1,3,2-dioxaborolane 
• 1325729-44-9 (R)-4,4,5,5-tetramethyl-2-(3-methyl-2-phenylbutyl)-1,3,2-dioxaborolane 
• 911806-53-6 4-methyl-2-phenylpentanal 
• 1073897-81-0 2-isobutyl-2-phenyloxirane 
• 1241903-39-8 (E)-4-methyl-2-phenyl-1-pentenyl(pinacol)borane 
• 4355-51-5 2,4-dimethyl-2-phenyl-valeronitrile 

Relevant articles and documents

Electrochemical-induced radical allylation via the fragmentation of alkyl 1,4-dihydropyridines

Aldehydes are abundant chemical motifs presented in natural products and pharmaceuticals. As a radical precursor, its application is limited. Dihydropyridines (DHPs) can act as masked aldehydes, providing alkyl radicals under the activation of Lewis acid, heat, SET oxidant and light irradiation. Herein, we report the direct activation of 4-alkyl DHPs via single electron transfer at the anode. C–C bond homolysis at the C4-position of DHP generated the corresponding alkyl radical, which was captured subsequently by 2-phenyl and 2-ethoxy carbonyl allyl bromide. The following intramolecular elimination reaction afforded 20 different radical allylation products bearing various alkyl substituents with yields up to 92%.

Unlocking the Accessibility of Alkyl Radicals from Boronic Acids through Solvent-Assisted Organophotoredox Activation

Despite their prevalence in organic synthesis, the application of boronic acids (BAs) as alkyl radical precursors in visible-light-assisted photocatalyzed reactions has been limited by their high oxidation potential. This study demonstrates the prominent

Electron-deficient olefin ligands enable generation of quaternary carbons by Ni-catalyzed cross-coupling

A Ni-catalyzed Negishi cross-coupling with 1,1-disubstituted styrenyl aziridines has been developed. This method delivers valuable β-substituted phenethylamines via a challenging reductive elimination that affords a quaternary carbon. A novel electron-deficient olefin ligand, Fro-DO, proved crucial for achieving high rates and chemoselectivity for C-C bond formation over β-H elimination. This ligand is easy to access, is stable, and presents a modular framework for reaction discovery and optimization. We expect that these attributes, combined with the fact that the ligands impart distinct electronic properties to a metal, will support the invention of new transformations not previously possible using established ligands.