38258-74-1

Basic information

• Product Name: 4-Methylcyclohexyl isocyanate
• Synonyms: 1-Isocyanato-4-methyl-cyclohexane;4-methylcyclohexyl isocyanate;isocyanic acid 4-methylcyclohexyl ester;Cyclohexane,1-Isocyanato-4-Methyl-
• CAS NO: 38258-74-1
• Molecular Formula: C₈H₁₃NO
• Molecular Weight: 139.19
• Mol File: 38258-74-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 182°C
• Flash Point: 60°C
• Appearance: /
• Density: 1.04
• Vapor Pressure: 0.818mmHg at 25°C
• Refractive Index: 1.518
• CAS DataBase Reference: 4-Methylcyclohexyl isocyanate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methylcyclohexyl isocyanate(38258-74-1)
• EPA Substance Registry System: 4-Methylcyclohexyl isocyanate(38258-74-1)

Safety Data

• Hazardous Substances Data: 38258-74-1(Hazardous Substances Data)

Usage

General Description

4-Methylcyclohexyl isocyanate is a chemical compound used primarily in the production of various polymers, such as polyurethane. It falls under the organic compound category and has the molecular formula of C8H13NO. This isocyanate compound has a methyl functional group attached to a cyclohexyl ring. Like all isocyanates, it reacts with compounds that contain active hydrogen atoms, such as water and alcohols, to form urea-like products, and with amines to form ureas. It is essential to handle it with care due to its high reactivity and potential harmfulness if ingested or inhaled.

InChI:InChI=1/C8H13NO/c1-7-2-4-8(5-3-7)9-6-10/h7-8H,2-5H2,1H3/t7-,8-

Upstream product

• 4331-54-8 4-methylcyclohexanecarboxylic acid 

Downstream Products

• 24477-26-7 3-methyl-isoxazole-5-carboxylic acid 4-[(4-methyl-cyclohexylcarbamoyl)-sulfamoyl]-phenethylamide 
• 25200-69-5 C₂₃H₂₉N₃O₄S 
• 2235-64-5 C₂₂H₂₆ClN₃O₄S 
• 52068-97-0 C₂₄H₃₂N₄O₄S 
• 52069-04-2 C₂₅H₃₄N₄O₄S 
• 52068-88-9 C₂₅H₃₄N₄O₄S 
• 52069-12-2 C₂₇H₃₈N₄O₄S 
• 22781-47-1 C₂₅H₃₄N₄O₄S 
• 52069-08-6 C₂₅H₃₃ClN₄O₄S 
• 52068-66-3 C₂₅H₃₂N₄O₅S 
• 22781-67-5 C₂₇H₃₈N₄O₄S 
• 22782-20-3 C₂₄H₃₁ClN₄O₄S 
• 22781-53-9 C₂₅H₃₄N₄O₅S 
• 52068-74-3 C₂₆H₃₄N₄O₅S 

Relevant articles and documents

TRIAZOLONE COMPOUNDS AND USES THEREOF

The invention disclosed herein is directed to compounds of Formula (la) and (lb) and pharmaceutically acceptable salts thereof, which are useful in the treatment of prostate, breast, colon, pancreatic, human chronic lymphocyticδ leukemia, melanoma and other cancers. The invention also comprises pharmaceutical compositions comprising a therapeutically effective amount of compound of Formula (la) or (lb), or a pharmaceutically acceptable salt thereof. The invention disclosed herein is also directed to methods of treating prostate, breast, ovarian, liver, kidney, colon, pancreatic, human chronic lymphocytic leukemia, melanoma and other cancers. The invention disclosed herein is further directed to methods of treating prostate, breast, colon, pancreatic, chronic lymphocytic leukemia, melanoma and other cancers comprising administration of a therapeutically effective amount of a compound which is a dual antagonist of PPARα and PPARδ. The compounds and pharmaceutical compositions of the invention are also useful in the treatment of viral infections, such as HCV infections and HIV infections. The invention disclosed herein is also directed to a methods of preventing the onset of and/or recurrence of acute and chronic myeloid leukemia, as well as other cancers, comprising administration of a herapeutically effective amount of a dual antagonist of PPARα and PPARδ.