38275-41-1 Usage
Description
Methyl 2-(methylthio)pyrimidine-5-carboxylate is an organic compound that belongs to the pyrimidine family. It is characterized by the presence of a methylthio group and a carboxylate group attached to the pyrimidine core. Methyl 2-(methylthio)pyrimidine-5-carboxylate serves as an important intermediate in the synthesis of various pyrimidine-based molecules, which have a wide range of applications in the pharmaceutical and chemical industries.
Uses
Used in Pharmaceutical Industry:
Methyl 2-(methylthio)pyrimidine-5-carboxylate is used as a key intermediate for the synthesis of pyrimidine derivatives. These derivatives are known for their diverse biological activities, including antiviral, anticancer, and anti-inflammatory properties. Methyl 2-(methylthio)pyrimidine-5-carboxylate plays a crucial role in the development of new drugs targeting various diseases.
Used in Chemical Industry:
In the chemical industry, Methyl 2-(methylthio)pyrimidine-5-carboxylate is utilized for the preparation of pyrimidines through cyclocondensation of amidinium with formylpropenolate. This process allows for the creation of a variety of pyrimidine-based compounds with potential applications in different fields, such as agrochemicals, dyes, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 38275-41-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,2,7 and 5 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 38275-41:
(7*3)+(6*8)+(5*2)+(4*7)+(3*5)+(2*4)+(1*1)=131
131 % 10 = 1
So 38275-41-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H8N2O2S/c1-11-6(10)5-3-8-7(12-2)9-4-5/h3-4H,1-2H3
38275-41-1Relevant articles and documents
Reaction of esters of 2-substituted 5-pyrimidinecarboxylic acids with hydrazine hydrate
Tumkevicius,Yakubkene,Vainilavicius
, p. 1334 - 1336 (1999)
The reaction of methyl esters of 2-substituted 5-pyrimidinecarboxylic acids with hydrazine hydrate at 0-5°C results in the nucleophilic substitution of readily eliminating groups (Cl, CH3O, CH3S) at the position 2 of the pyrimidine r
A general procedure for the synthesis of 2-substituted pyrimidine-5-carboxylic esters
Zhichkin, Pavel,Fairfax, David J.,Eisenbeis, Shane A.
, p. 720 - 722 (2007/10/03)
A method for the synthesis of 2-substituted pyrimidine-5-carboxylic esters is described. The sodium salt of 3,3-dimethoxy-2-methoxycarbonylpropen-1-ol (3) has been found to react with a variety of amidinium salts to afford the corresponding 2-substituted pyrimidine-5-carboxylic esters.
