38320-48-8

Basic information

• Product Name: (2S)-2-(acetylamino)-N-[(2S)-2-{[(1S)-3-chloro-1-methyl-2-oxopropyl]amino}propanoyl]propanamide (non-preferred name)
• CAS NO: 38320-48-8
• Molecular Formula: C₁₂H₂₀ClN₃O₄
• Molecular Weight: 305.7579
• Mol File: 38320-48-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 520.7°C at 760 mmHg
• Flash Point: 268.7°C
• Density: 1.203g/cm³
• Vapor Pressure: 6.08E-11mmHg at 25°C
• Refractive Index: 1.488
• CAS DataBase Reference: (2S)-2-(acetylamino)-N-[(2S)-2-{[(1S)-3-chloro-1-methyl-2-oxopropyl]amino}propanoyl]propanamide (non-preferred name)(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-2-(acetylamino)-N-[(2S)-2-{[(1S)-3-chloro-1-methyl-2-oxopropyl]amino}propanoyl]propanamide (non-preferred name)(38320-48-8)
• EPA Substance Registry System: (2S)-2-(acetylamino)-N-[(2S)-2-{[(1S)-3-chloro-1-methyl-2-oxopropyl]amino}propanoyl]propanamide (non-preferred name)(38320-48-8)

Safety Data

• Hazardous Substances Data: 38320-48-8(Hazardous Substances Data)

Upstream product

• 19245-87-5 (S)-2-((S)-2-acetamidopropanamido)propanoic acid 
• 51152-30-8 H-AlaCH₂Cl, HBr 
• 30802-26-7 N-acetyl-L-alanyl-L-alanine methyl ester 

Relevant articles and documents

Thermitase - A Thermostable Serine Protease. II. Synthesis of Substrate Analogous Peptide Chloromethyl Ketones as Irreversibly Acting Inhibitors

The preparation of dipeptide to pentapeptide chloromethyl ketones of alanine with variation of the amino acid in the P1 and P2 position of the peptides is described.The synthesis is performed by fragment condensation of N-acylated amino acids or peptides with the unprotected chloromethyl ketone derivatives of amino acids and peptides, respectively.Some examples of enzyme inactivation by peptide chloromethyl ketones are discussed.