38339-06-9 Usage
Description
Homovanillic Acid Sulfate is a metabolite of Dihydroxyphenylacetic Acid (DOPAC) produced by the action of catechol O-methyltransferase. It is an off-white to light beige solid and has been identified for its potential applications in various fields.
Uses
Used in Diagnostic Applications:
Homovanillic Acid Sulfate is used as a diagnostic tool for Alzheimer's disease. It aids in the detection and monitoring of the disease's progression, providing valuable insights for medical professionals and patients.
Used in Pharmaceutical Research:
As a metabolite of DOPAC, Homovanillic Acid Sulfate holds potential for further research and development in the pharmaceutical industry. Its role in the metabolism of neurotransmitters may lead to the discovery of new treatments for various neurological conditions.
Used in Chemical Analysis:
Due to its chemical properties, Homovanillic Acid Sulfate can be employed in chemical analysis and laboratory settings. It may serve as a reference compound or be utilized in the synthesis of other compounds for research purposes.
Check Digit Verification of cas no
The CAS Registry Mumber 38339-06-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,3,3 and 9 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 38339-06:
(7*3)+(6*8)+(5*3)+(4*3)+(3*9)+(2*0)+(1*6)=129
129 % 10 = 9
So 38339-06-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H10O7S.2Na/c1-15-8-4-6(5-9(10)11)2-3-7(8)16-17(12,13)14;;/h2-4H,5H2,1H3,(H,10,11)(H,12,13,14);;/q;2*+1/p-2/rC9H9NaO7S.Na/c1-15-8-4-6(5-9(11)12)2-3-7(8)16-18(13,14)17-10;/h2-4H,5H2,1H3,(H,11,12);/q;+1/p-1
38339-06-9Relevant articles and documents
A Convenient Synthesis of Hydroxytyrosol Monosulfate Metabolites
Gomes, Vania Patrícia Martins,Torres, Carmen,Rodríguez-Borges, José Enrique,Paiva-Martins, Fátima
, p. 9565 - 9571 (2015/11/17)
The growing interest in the bioactivity of natural polyphenols and of their metabolites requires metabolites to be used in bioassays and as standards in research protocols. We report here on the synthesis of several hydroxytyrosol metabolite monosulfates achieved using a simplified protocol with improved yields. A synthetic solution based on avoidance of high temperature conditions during the synthesis and of low pressure conditions during purification has been established. Monosulfates of several phenolic compounds, namely, hydroxytyrosol, hydroxytyrosol acetate, homovanillyl alcohol, homovanillyl alcohol acetate, homovanillic acid, ferulic acid, and 3,4-dihydroxyphenylethanoic acid, were efficiently synthesized in 1-2 steps in good yield and isolated using simple procedures. The proposed protocol was shown to be relatively rapid, efficient, cheap, and widely applicable to a number of catechol scaffolds.
