38372-01-9

Basic information

• Product Name: Phenol, 2-[5-(4-chlorophenyl)-1-phenyl-1H-pyrazol-3-yl]-
• CAS NO: 38372-01-9
• Molecular Formula: C21H15ClN2O
• Molecular Weight: 346.816
• Mol File: 38372-01-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Phenol, 2-[5-(4-chlorophenyl)-1-phenyl-1H-pyrazol-3-yl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2-[5-(4-chlorophenyl)-1-phenyl-1H-pyrazol-3-yl]-(38372-01-9)
• EPA Substance Registry System: Phenol, 2-[5-(4-chlorophenyl)-1-phenyl-1H-pyrazol-3-yl]-(38372-01-9)

Safety Data

• Hazardous Substances Data: 38372-01-9(Hazardous Substances Data)

Upstream product

• 7327-78-8 2-[1-(2-phenylhydrazino)ethyl]phenol 
• 43016-14-4 4-chloro-2'-hydroxychalcone dibromide 
• 100-63-0 phenylhydrazine 
• 93514-36-4 4'-chloroflavanone 
• 104-88-1 4-chlorobenzaldehyde 
• 579-74-8 2-Methoxyacetophenone 
• 872057-29-9 3-(4-chlorophenyl)-1-(2-methoxyphenyl)-2-propen-1-one 
• 1426534-27-1 C₂₂H₁₉ClN₂O 
• 1426534-12-4 C₂₂H₁₇ClN₂O 
• 3033-96-3 4-chloro-2'-hydroxychalcone 
• 118-93-4 o-hydroxyacetophenone 

Downstream Products

• 1426533-84-7 C₂₃H₁₇ClN₂O₃ 
• 1426533-85-8 C₂₅H₂₁ClN₂O₃ 
• 1426533-86-9 C₂₆H₂₃ClN₂O₃ 
• 1426533-87-0 C₂₈H₂₇ClN₂O₃ 

Relevant articles and documents

Structure-guided design, synthesis and in vitro evaluation of a series of pyrazole-based fatty acid binding protein (FABP) 3 ligands

We designed a series of pyrazole-based carboxylic acids as candidate ligands of heart fatty acid binding protein (H-FABP, or FABP3), based on a comparison of the X-ray crystallographic structures of adipocyte fatty acid binding protein (FABP4)-selective inhibitor (BMS309403) complex and FABP3-elaidic acid complex. Some of the synthesized compounds exhibited dual FABP3/4 ligand activity, and some exhibited selectivity for FABP3.

Synthesis of pyrazole and isoxazole in triethanolamine medium

Reactions of 2′-hydroxy chalcone dibromides 2a-1 with phenyl hydrazine and hydrazine hydrate afford pyrazoles 1a-1 and with hydroxylamine hydrochloride give isoxazoles 5a-f in triethanolamine medium. Similarly reaction of β-diketone 3b-e with phenyl hydra

SYNTHESIS OF SOME ISOMERIC PYRAZOLES

The syntheses of 3-o-hydroxyphenyl-1,5-diphenylpyrazoles (III) and 1,3-diphenyl-5-o-hydroxyphenylpyrazoles (V) by the oxidation of corresponding pyrazolines (II) with manganese dioxide and by the reaction of phenylhydrazine with 2'-hydroxychalcone dibromi