384346-98-9

Basic information

• Product Name: methyl 3-O-tert-butyldimethylsilyl-4,6-O-p-methoxybenzylidene-2-deoxy-2-trifluoroacetamido-β-D-glucopyranoside
• Synonyms: methyl 3-O-tert-butyldimethylsilyl-4,6-O-p-methoxybenzylidene-2-deoxy-2-trifluoroacetamido-β-D-glucopyranoside
• CAS NO: 384346-98-9
• Molecular Weight: 521.606
• Mol File: 384346-98-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 3-O-tert-butyldimethylsilyl-4,6-O-p-methoxybenzylidene-2-deoxy-2-trifluoroacetamido-β-D-glucopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-O-tert-butyldimethylsilyl-4,6-O-p-methoxybenzylidene-2-deoxy-2-trifluoroacetamido-β-D-glucopyranoside(384346-98-9)
• EPA Substance Registry System: methyl 3-O-tert-butyldimethylsilyl-4,6-O-p-methoxybenzylidene-2-deoxy-2-trifluoroacetamido-β-D-glucopyranoside(384346-98-9)

Safety Data

• Hazardous Substances Data: 384346-98-9(Hazardous Substances Data)

Upstream product

• 74-88-4 methyl iodide 
• 340320-92-5 tert-butyl(((2R,4aR,8R,8aR)-2-(4-methoxyphenyl)-4,4a,8,8a-tetrahydropyrano[3,2-d][1,3]dioxin-8-yl)oxy)dimethylsilane 
• 273749-60-3 phenyl 4,6-O-(4-methoxybenzylidene)-1-thio-β-D-glucopyranoside 
• 187880-20-2 2,6-anhydro-5-deoxy-1,3-O-(4-methoxybenzylidene)-D-arabino-hex-5-enitol 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 40299-08-9 methyl 2-deoxy-2-trifluoroacetamido-β-D-glucopyranoside 
• 3946-01-8 methyl N-acetyl-β-D-glucosaminide 

Relevant articles and documents

Stereoselective synthesis of [13C]methyl 2-[15N]amino-2-deoxy-beta-D-glucopyranoside derivatives.

Efficient syntheses of three [13C]methyl 2-[15N]amino-2-deoxy-beta-D-glucopyranoside derivatives are described. Amination of the D-glucal with (saltmen)Mn(15N) proceeded with 11:1 stereoselectivity favoring the gluco configuration; subsequent methylation of the [15N]lactol using [13C]iodomethane and silver(I) oxide afforded the doubly labeled beta glucoside in high yield. This compound served as the common precursor for three [13C]methyl 2-[15N]aminoglucosides: (2-[15N]trifluoroacetyl-), (2-[15N]acetyl-), and (2-[15N]azido-). Selected heteronuclear coupling constants are reported.