3847-27-6

Basic information

• Product Name: Kanamycin A sulphate
• Synonyms: Kanamycin A sulfate;Kanamycin disulfate salt from Streptomyces kanamyceticus;kanamycin A sulphate;Canamycin A disulfate;canamycin monosulfate;kanA sulfate;kanamycin A monosulfate
• CAS NO: 3847-27-6
• Molecular Formula: C₁₈H₃₈N₄O₁₅S
• Molecular Weight: 582.584
• Mol File: 3847-27-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 809.5°Cat760mmHg
• Flash Point: 443.4°C
• Density: g/cm³
• CAS DataBase Reference: Kanamycin A sulphate(CAS DataBase Reference)
• NIST Chemistry Reference: Kanamycin A sulphate(3847-27-6)
• EPA Substance Registry System: Kanamycin A sulphate(3847-27-6)

Safety Data

• Hazardous Substances Data: 3847-27-6(Hazardous Substances Data)

Upstream product

• 4696-76-8 kananmycin B 

Downstream Products

• 100899-85-2 C₃₅H₅₂N₆O₁₇S^(2-)*H₂O₄S*2Na⁽¹⁺⁾ 
• 20744-51-8 6-O-[(3-deoxy-3-amino)-α-D-glucopyranosyl]-2-deoxy-streptamine 
• 953395-50-1 1,3,6',3''-tetra-N-(tert-butoxycarbonyl)-6''-azido-6''-deoxy-kanamycin A 
• 80860-34-0 di-tert-butyl ((1S,3R,4S,5R,6R)-4-(((2S,3R,4S,5S,6R)-4-((tert-butoxycarbonyl)amino)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-6-(((2R,3R,4S,5S,6R)-6-(((tert-butoxycarbonyl)amino)methyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)-5-hydroxycyclohexane-1,3-diyl)dicarbamate 
• 59-01-8 kanamycin A 
• 1037515-73-3 1,3,6',3”-tetra-azido-kanamycin A 

Relevant articles and documents

The last step of kanamycin biosynthesis: Unique deamination reaction catalyzed by the α-ketoglutarate-dependent nonheme iron dioxygenase KanJ and the NADPH-dependent reductase KanK

Mystery solved: Using heterologous expression, the activities of two enzymes exclusively belonging to the kanamycin biosynthetic pathway have been identified in vitro. A distinctive reaction mechanism (see scheme) to produce kanamycin is proposed and the previously unknown catalytic deamination activity of KanJ dioxygenase is uncovered. Copyright