384820-96-6Relevant articles and documents
Synthesis and antibacterial activity of 5- and 6-hydroxy substituted 4-aminoquinolines and derivatives
Meyer,Lemcke,Geffken,Kaulfers
, p. 691 - 695 (2007/10/03)
The synthesis and antimicrobial activity of 4-amino-8-methylquinolines 8, 11 substituted with a hydroxy- or methoxy-group at 5- and at 6-position have been investigated. The title compounds could be prepared by a six-step procedure according to the literature starting from commercially available anilines 1. The novel 4-aminoquinolines 8,11 exhibited slight antibacterial activity against Gram-positive and Gram-negative bacteria.