384830-08-4 Usage
Description
(3R)-3-(IodoMethyl)-1-Boc-piperidine, also known as Boc-protected iodomethylpiperidine, is a chemical compound with the molecular formula C12H21INO2. It features a piperidine ring with a Boc (tert-butoxycarbonyl) protecting group and an iodomethyl functional group attached. (3R)-3-(IodoMethyl)-1-Boc-piperidine is significant in the field of medicinal chemistry and drug discovery due to its versatile reactivity and its presence in various drug-like molecules.
Uses
Used in Pharmaceutical Synthesis:
(3R)-3-(IodoMethyl)-1-Boc-piperidine is used as a building block for the preparation of various pharmaceutical compounds and bioactive molecules. The Boc group serves to protect the amine functionality of the piperidine ring, allowing for the introduction of new functionalities through the iodomethyl group, which can undergo various reactions.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (3R)-3-(IodoMethyl)-1-Boc-piperidine is utilized as a key intermediate for the development of new drugs. Its presence in drug-like molecules makes it a valuable component in the synthesis of potential therapeutic agents.
Used in Drug Discovery:
(3R)-3-(IodoMethyl)-1-Boc-piperidine plays a crucial role in drug discovery, as its versatile reactivity allows for the creation of diverse molecular structures with potential therapeutic properties. Researchers can exploit the compound's functional groups to design and synthesize novel drug candidates.
Check Digit Verification of cas no
The CAS Registry Mumber 384830-08-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,8,4,8,3 and 0 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 384830-08:
(8*3)+(7*8)+(6*4)+(5*8)+(4*3)+(3*0)+(2*0)+(1*8)=164
164 % 10 = 4
So 384830-08-4 is a valid CAS Registry Number.
384830-08-4Relevant articles and documents
RAS INHIBITORS
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Paragraph 1354-1355, (2021/05/07)
The disclosure features macrocyclic compounds, and pharmaceutical compositions and protein complexes thereof, capable of inhibiting Ras proteins, and their uses in the treatment of cancers.
Synthesis of potent and highly selective inhibitors of human tryptase
Slusarchyk, William A.,Bolton, Scott A.,Hartl, Karen S.,Huang, Ming-Hsing,Jacobs, Glenn,Meng, Wei,Ogletree, Martin L.,Pi, Zulan,Schumacher, William A.,Seiler, Steven M.,Sutton, James C.,Treuner, Uwe,Zahler, Robert,Zhao, Guohua,Bisacchi, Gregory S.
, p. 3235 - 3238 (2007/10/03)
The serine protease tryptase has been implicated in allergic and inflammatory diseases and associated with asthma. The synthesis and SAR of a series of N1-activated-4-carboxy azetidinones are described, resulting in identification of BMS-363131 (2) as a potent inhibitor of human tryptase (IC503000-fold) for tryptase versus related serine proteases including trypsin.
