3853-06-3 Usage
Description
METHYL 3-(DIMETHYLAMINO)PROPIONATE is an organic compound that serves as a reagent in chemical synthesis processes. It is characterized by its ability to react with lithium diisopropylamide, a common lithium amide used in organic synthesis, to form lithium enolates. These lithium enolates are versatile intermediates in organic chemistry, facilitating a range of reactions such as aldol condensations, Michael additions, and other carbon-carbon bond-forming processes.
Uses
Used in Chemical Synthesis:
METHYL 3-(DIMETHYLAMINO)PROPIONATE is used as a reagent for the synthesis of lithium enolates through its reaction with lithium diisopropylamide. This application is crucial for facilitating various organic reactions that require the formation of enolate anions, which are key intermediates in the construction of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, METHYL 3-(DIMETHYLAMINO)PROPIONATE plays a significant role in the synthesis of complex drug molecules. The ability to generate lithium enolates from this compound allows chemists to perform selective and efficient reactions that are essential for the development of new pharmaceutical agents.
Used in Research and Development:
METHYL 3-(DIMETHYLAMINO)PROPIONATE is also utilized in research and development settings, where it aids in the exploration of new synthetic pathways and the optimization of existing ones. Its role in the formation of lithium enolates makes it a valuable tool for advancing the field of organic chemistry and the discovery of novel compounds with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 3853-06-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,8,5 and 3 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 3853-06:
(6*3)+(5*8)+(4*5)+(3*3)+(2*0)+(1*6)=93
93 % 10 = 3
So 3853-06-3 is a valid CAS Registry Number.
InChI:InChI=1/C6H13NO2/c1-7(2)5-4-6(8)9-3/h4-5H2,1-3H3
3853-06-3Relevant articles and documents
Tandem conjugate addition-aldol reaction to α,β-unsaturated esters and ketones using titanium amide
Hosomi, Akira,Yanagi, Toshiharu,Hojo, Makoto
, p. 2371 - 2374 (2007/10/02)
Titanium dialkylamide, readily available, adds to a α,β-unsaturated esters and ketones in a conjugate addition mode to give ester and ketone enolates, respectively, which are successively quenched with electrophiles such as aldehydes and acetals. The aldol products can be readily converted to the corresponding deaminated or dehydrated derivatives selectively.
