385442-59-1Relevant articles and documents
Synthesis and microbiological activity of some 4-butyl-2H-benzo[1,4]thiazin-3-one derivatives
De M. Guarda,Perrissin, M,Thomasson, F,Ximenes,Galdino,Pitta,Luu-Duc, C
, p. 689 - 693 (2001)
The synthesis and physicochemical properties of 4-butyl-2H-benzo[1,4]thiazin-3-one derivatives are described. These new compounds were synthesised by alkylation in 4-N position and acylation and/or alkylation of 6-NH2 by phase transfer catalysis. Acid hydrolysis of 6-alkylacylamino group yielded 6-alkylamino-4-butyl-2H-benzo[1,4]thiazin-3-ones. The antimicrobial in vitro activity was determined on five compounds. Copyright