38603-53-1

Basic information

• Product Name: Benzamide, N-[[[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]amino]thioxomethyl]-
• CAS NO: 38603-53-1
• Molecular Formula: C15H18N4OS2
• Molecular Weight: 334.466
• Mol File: 38603-53-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzamide, N-[[[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]amino]thioxomethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N-[[[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]amino]thioxomethyl]-(38603-53-1)
• EPA Substance Registry System: Benzamide, N-[[[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]amino]thioxomethyl]-(38603-53-1)

Safety Data

• Hazardous Substances Data: 38603-53-1(Hazardous Substances Data)

Upstream product

• 532-55-8 Benzoyl isothiocyanate 
• 38585-67-0 4-{[(2-aminoethyl)thio]methyl}-5-methylimidazole 
• 38585-67-0 4-methyl-5-<(2-aminoethyl)-thiomethyl>-imidazole 

Relevant articles and documents

Histamine analogues. 32nd communication: synthesis and pharmacology of sopromidine, a potent and stereoselective isomer of the achiral H2-agonist impromidine

Synthesis and pharmacology of sopromidine ((R)-7) and (S)-7, 2 position isomers of impromidine derived from the enantiomeric α-methylhistamines, are reported.The enantiomers of 7 show high stereoselectivity at the atrial H2-receptor of the guinea-pig. (R)-7 is revealed to be a full H2-agonist with 7.4-fold potency relative to histamine, while (S)-7 is a competitive H2-antagonist. chiral H2-agonists / histamine H2-receptor / impromidine analogues / α-methylhistamine

PHARMACOLOGICALLY ACTIVE THIOUREA AND UREA COMPOUNDS

The compounds are substituted thioalkyl-, aminoalkyl-and oxyalkyl-thioureas and ureas which are inhibitors of histamine activity.