38676-82-3Relevant articles and documents
The NMR studies on two new furostanol saponins from Agave sisalana leaves
Zou, Peng,Fu, Jing,Yu, He-Shui,Zhang, Jie,Kang, Li-Ping,Ma, Bai-Ping,Yan, Xian-Zhong
, p. 1090 - 1095 (2006)
The detailed NMR studies and full assignments of the 1H and 13C spectral data for two new furostanol saponins isolated from Agave sisalana leaves are described. Their structures were established using a combination of 1D and 2D NMR techniques including 1H, 13C, 1H-1H COSY, TOCSY, HSQC, HMBC and HSQC-TOCSY, and also FAB-MS spectrometry and chemical methods. The structures were established as (25S)-26-(β-D-glucopyranosyl)-22ξ-hydroxyfurost-12-one-3β-yl-O- α-L-rhamnopyranosyl-(1→4)-β-D-glucopyranosyl-(1→3) -O-[O-β-D-glucopyranosyl-(1→2)]-O-β-D-glucopyranosyl-(1→4) -β-D-galactopyranoside (1) and (25S)-26-(β-D-glucopyranosyl)-22ξ- hydroxyfurost-5-en-12-one-3ξ-yl-O-α-L-rhamnopyranosyl-(1→4) -β-D-glucopyranosyl-(1→3)-O-[O-β-D-glucopyranosyl-(1→2)] -O-β-D-glucopyranosyl-(1→4)-β-D-galactopyranoside (2). Copyright
Synthesis of a new cytotoxic cephalostatin/ritterazine analogue from hecogenin and 22-epi-hippuristanol
Poza, Javier Jesus,Rodriguez, Jaime,Jimenez, Carlos
scheme or table, p. 58 - 63 (2010/04/26)
A new cephalostatin/ritterazine analogue was prepared from the commercially available hecogenin acetate and the natural cytotoxic steroid 22-epi-hippuristanol. The method involved the reductive dimerization of enaminoketones (condensation of α-aminoketones) and condensation between an enaminoketone and an α-hydroxyketone. The new analogue showed higher cytotoxic activity than the cytotoxic 22-epi-hippuristanol against MDA-MB-231, A-549 and HT-29 cultured tumor cell lines.
STEROIDAL SAPONINS FROM CHLOROPHYTUM MALAYENSE
Xing-Cong, Li,Wang, De-Zu,Yang, Chong-Ren
, p. 3893 - 3898 (2007/10/02)
Four new steroidal saponins, chloromalosides A-D, were isolated from the rhizomes of Chlorophytum malayense.On the basis of detailed chemical and spectroscopic evidence, the structures of chloromalosides A-D were elucidated to be neohecogenin 3-O-β-D-glucopyranosyl(1->2)-3)>-β-D-glucopyranosyl(1->4)-β-D-galactopyranoside, 26-β-D-glucopyranosyl-22-hydroxy-25(S)-5α-furostane-3β,26-diol-3-O-β-D-glucopyranosyl(1->2)-3)>-β-D-glucopyranosyl(1->4)-β-D-galactopyranoside, neohecogenin 3-O-β-D-xylopyranosyl(1->3)-2)>-β-D-glucopyranosyl(1->4)-2)>-β-D-galactopyranoside and neotigogenin 3-O-β-D-xylopyranosyl(1->3)-2)>-β-D-glucopyranosyl(1->4)-2)>-β-D-galactopyranoside, respectively.