386768-88-3

Basic information

• Product Name: N'-(3-cyanobenzyl)-6-methoxy-N-[(4-methyl-1-piperidinyl)carbonyl]-2-naphthalenesulfonohydrazide
• Synonyms: N'-(3-cyanobenzyl)-6-methoxy-N-[(4-methyl-1-piperidinyl)carbonyl]-2-naphthalenesulfonohydrazide
• CAS NO: 386768-88-3
• Molecular Weight: 492.599
• Mol File: 386768-88-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N'-(3-cyanobenzyl)-6-methoxy-N-[(4-methyl-1-piperidinyl)carbonyl]-2-naphthalenesulfonohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: N'-(3-cyanobenzyl)-6-methoxy-N-[(4-methyl-1-piperidinyl)carbonyl]-2-naphthalenesulfonohydrazide(386768-88-3)
• EPA Substance Registry System: N'-(3-cyanobenzyl)-6-methoxy-N-[(4-methyl-1-piperidinyl)carbonyl]-2-naphthalenesulfonohydrazide(386768-88-3)

Safety Data

• Hazardous Substances Data: 386768-88-3(Hazardous Substances Data)

Upstream product

• 626-58-4 4-methylpiperidin 
• 439926-78-0 2-(3-cyanobenzyl)-2-[(4-methyl-1-piperidinyl)carbonyl]hydrazinium chloride 
• 386768-80-5 N'-[1-(3-Cyano-phenyl)-meth-(E)-ylidene]-hydrazinecarboxylic acid tert-butyl ester 
• 386768-84-9 tert-butyl 2-(3-cyanobenzyl)-2-[(4-methyl-1-piperidinyl)carbonyl]hydrazinecarboxylate 
• 386768-81-6 tert-butyl 2-(3-cyanobenzyl)hydrazine-1-carboxylate 
• 24964-64-5 3-Cyanobenzaldehyde 
• 56875-59-3 6-methoxy-naphthalene-2-sulfonyl chloride 
• 439926-99-5 4-methyl-piperidine-1-carboxylic acid N-(3-cyano-benzyl)-hydrazide 

Relevant articles and documents

Thrombin inhibitors built on an azaphenylalanine scaffold

A series of azaphenylalanine derivatives were investigated as novel thrombin inhibitors based on the prodrug principle. By systematic structural modifications we have identified optimal groups for this series that led us to potent inhibitors of thrombin i

Novel thrombin inhibitors with azaphenylalanine scaffold

In this paper the synthesis and antithrombotic activity of a series of novel thrombin inhibitors with azaphenylalanine scaffold are described. By systematic structural modifications for this series we have identified optimal groups for achieving nanomolar potency, that led to potent inhibitors of thrombin with Ki values up to 11 nM.