38681-73-1Relevant articles and documents
Discovery of memantyl urea derivatives as potent soluble epoxide hydrolase inhibitors against lipopolysaccharide-induced sepsis
Du, Fangyu,Sun, Wenjiao,Morisseau, Christophe,Hammock, Bruce D.,Bao, Xuefei,Liu, Qiu,Wang, Chao,Zhang, Tan,Yang, Hao,Zhou, Jun,Xiao, Wei,Liu, Zhongbo,Chen, Guoliang
, (2021/07/06)
Sepsis, a systemic inflammatory response, caused by pathogenic factors including microorganisms, has high mortality and limited therapeutic approaches. Herein, a new soluble epoxide hydrolase (sEH) inhibitor series comprising a phenyl ring connected to a
sEH inhibitor and preparation method and application thereof
-
Paragraph 0234; 0236; 0241-0242, (2020/07/28)
The invention provides an sEH inhibitor and a preparation method and application thereof, and relates to the technical field of endogenous active substance regulation and control. The sEH inhibitor provided by the invention has a structure as shown in a f
Benzamide therapeutics for the treatment of inflammatory bowel disease
-
, (2008/06/13)
Benzamides are disclosed to be useful for treating and preventing inflammatory bowel disease.