387-97-3 Usage
General Description
5-Fluoro-8-hydroxyquinoline is a chemical compound with the molecular formula C9H6FNO. It is a derivative of quinoline and features a fluorine atom at the 5-position and a hydroxyl group at the 8-position. 5-FLUORO-8-HYDROXYQUINOLINE is commonly used as a ligand for metal ions in coordination chemistry, and it has been studied for its potential pharmaceutical applications. It exhibits antimicrobial and antifungal properties and has been investigated for its potential as an antitumor agent. Its ability to chelate metal ions makes it useful in analytical chemistry and as a potential component in the development of new materials.
Check Digit Verification of cas no
The CAS Registry Mumber 387-97-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,8 and 7 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 387-97:
(5*3)+(4*8)+(3*7)+(2*9)+(1*7)=93
93 % 10 = 3
So 387-97-3 is a valid CAS Registry Number.
InChI:InChI=1/C12H2F8/c13-3-1-4(14)10(18)7(9(3)17)8-11(19)5(15)2-6(16)12(8)20/h1-2H
387-97-3Relevant articles and documents
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O'Dom,Fernando
, p. 844 (1966)
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Quinoline synthesis by improved Skraup-Doebner-Von Miller reactions utilizing acrolein diethyl acetal
Ramann, Ginelle A.,Cowen, Bryan J.
supporting information, p. 6436 - 6439 (2015/11/16)
A robust synthetic method has been developed as an improvement to the venerable Skraup-Doebner-Von Miller reaction providing access to various quinoline products. The straightforward procedure utilizes acrolein diethyl acetal as a three-carbon annulation partner with aniline substrates in a monophasic, organic solvent-free reaction medium. Differentially substituted aniline precursors were found to be compatible with the reaction conditions and the corresponding quinoline products are isolated in moderate to good yields.
