38701-07-4Relevant articles and documents
Study on the selectivity in the electrophilic monofluorination of 2,3-allenoates with Selectfluor: An efficient synthesis of 4-fluoro-2(5H)-furanones and 3-fluoro-4-oxo-2(E)-alkenoates
Lue, Bo,Fu, Chunling,Ma, Shengming
supporting information; experimental part, p. 274 - 281 (2010/04/24)
Different from the reaction of 2,3-allenoic acids with Selectfluor, 4-fluoro-2(5H)-furanones and (E)-3-fluoro-4-oxo-2-alkenoates were highly selectively generated from 2,4-disubstituted 2,3-allenoates with Selectfluor under different conditions in moderate yields. The reaction of 2, 4, 4-trisubstituted 2,3-allenoates afforded the corresponding 4-fluoro-2(5H)-furanones highly selectively with up to 95% yield under different conditions. The scope of the substrates has been carefully explored. Due to the more readily availability of 2,3-allenoates as compared to 2,3-allenoic acids, new 4-fluoro-2(5H)furanones were prepared. Based on the isolation and characterization of the minor fluorohydroxylation product E-5m, a mechanism has been proposed. The Royal Society of Chemistry 2010.
Eine einfache Allencarbonsaeureester-Synthese mittels der Wittig-Reaktion
Lang, Robert W.,Hansen, Hans-Juergen
, p. 438 - 455 (2007/10/02)
A simple one-pot synthesis of variously substituted α-allenic esters (7-23, cf.Scheme 4) is described.Either of the phosphonium salts 1 and 2 or the phosphoranes 3-6 in methylene chloride (or acetonitrile) when treated with acid chlorides at room temperat
