388071-37-2

Basic information

• Product Name: (3S)-(3-amino-2-hydroxy-4-phenyl-butyl)-(3-methoxy-benzyl)-carbamic acid tert-butyl ester
• Synonyms: (3S)-(3-amino-2-hydroxy-4-phenyl-butyl)-(3-methoxy-benzyl)-carbamic acid tert-butyl ester
• CAS NO: 388071-37-2
• Molecular Weight: 400.518
• Mol File: 388071-37-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (3S)-(3-amino-2-hydroxy-4-phenyl-butyl)-(3-methoxy-benzyl)-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (3S)-(3-amino-2-hydroxy-4-phenyl-butyl)-(3-methoxy-benzyl)-carbamic acid tert-butyl ester(388071-37-2)
• EPA Substance Registry System: (3S)-(3-amino-2-hydroxy-4-phenyl-butyl)-(3-methoxy-benzyl)-carbamic acid tert-butyl ester(388071-37-2)

Safety Data

• Hazardous Substances Data: 388071-37-2(Hazardous Substances Data)

Upstream product

• 658691-01-1 (3S,2R) (3-azido-2-hydroxy-4-phenyl-butyl)-(3-methoxy-benzyl)-carbamic acid tert-butyl ester 
• 128018-44-0 N-benzyloxycarbonyl-3(S)-amino-1,2(S)epoxy-4-phenylbutane 
• 5071-96-5 3-METHOXYBENZYLAMINE 
• 388071-35-0 benzyl (1S,2R)-1-benzyl-2-hydroxy-3-[(3-methoxybenzyl)amino]propylcarbamate 
• 388071-36-1 {1-benzyl-3-[tert-butoxycarbonyl-(3-methoxy-benzyl)-amino]-2-hydroxy-propyl}-carbamic acid benzyl ester 

Downstream Products

• 658691-57-7 C₄₉H₆₂N₄O₈ 
• 388071-39-4 tert-butyl (2R,3S)-3-({3-cyano-5-[(dipropylamino)carbonyl]benzoyl}amino)-2-hydroxy-4-phenylbutyl-(3-methoxybenzyl)carbamate 

Relevant articles and documents

Design of potent inhibitors of human β-secretase. Part 1

We describe a novel series of potent inhibitors of human β-secretase. These compounds possess the hydroxyethyl amine transition state isostere. A 2.5 A crystal structure of inhibitor 32 bound to BACE is provided.

SUBSTITUTED HYDROXYETHYLAMINES

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