3887-02-3

Basic information

• Product Name: N-METHYL METHACRYLAMIDE
• Synonyms: N-METHYL METHYLACRYLAMIDE;N-METHYL METHACRYLAMIDE;N,2-dimethylacrylamide;n-methylmethacrylamide(stabilizedwithhq);N,2-Dimethyl-2-propenamide;N,2-Dimethylpropenamide;N,2-dimethylprop-2-enamide;N-Methylmethacrylamide (stabilized with HQ)
• CAS NO: 3887-02-3
• Molecular Formula: C₅H₉NO
• Molecular Weight: 99.13
• EINECS: 223-428-1
• Product Categories: monomer
• Mol File: 3887-02-3.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 88°C 3,5mm
• Flash Point: 113.7 °C
• Appearance: /
• Density: 0.97
• Vapor Pressure: 0.121mmHg at 25°C
• Refractive Index: 1.4720-1.4760
• Storage Temp.: 0-10°C
• PKA: 15.25±0.46(Predicted)
• CAS DataBase Reference: N-METHYL METHACRYLAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-METHYL METHACRYLAMIDE(3887-02-3)
• EPA Substance Registry System: N-METHYL METHACRYLAMIDE(3887-02-3)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 3887-02-3(Hazardous Substances Data)

Usage

General Description

N-Methyl methacrylamide is a chemical compound with the formula C5H9NO2. It is a colorless liquid that is highly flammable and soluble in water. N-Methyl methacrylamide is commonly used as a monomer in the production of polymers and copolymers, particularly in the manufacturing of plastics, resins, and adhesives. It can also be used in the synthesis of specialty chemicals and pharmaceuticals. Due to its potential health hazards and environmental impacts, proper handling and disposal practices must be followed when working with N-Methyl methacrylamide.

InChI:InChI=1/C5H9NO/c1-4(2)5(7)6-3/h1H2,2-3H3,(H,6,7)

Upstream product

• 61101-76-6 α-acetoxy-isobutyric acid methylamide 
• 80-62-6 methacrylic acid methyl ester 
• 74-89-5 methylamine 
• 79-41-4 poly(methacrylic acid) 
• 920-46-7 Methacryloyl chloride 
• 39961-72-3 α-hydroxy isobutyric acid N-methyl amide 
• 624-83-9 methyl isocyanate 
• 760-93-0 methacryloyl anhydride 
• 593-51-1 methylamine hydrochloride 

Downstream Products

• 111875-30-0 N-benzoylformyl-N-methylmethacrylamide 
• 110613-79-1 (4R,5S)-N-methyl-5-<<(tert-butyloxy)carbonyl>amino>-6-cyclohexyl-4-hydroxyhex-1-ene-2-carboxamide 
• 110613-70-2 (4S,5S)-N-methyl-5-<<(tert-butyloxy)carbonyl>amino>-6-cyclohexyl-4-hydroxyhex-1-ene-2-carboxamide 
• 221286-63-1 ((S)-2-Hydroxy-1-isopropyl-4-methylcarbamoyl-pent-4-enyl)-carbamic acid benzyl ester 
• 15542-96-8 1,3-Dimethyl-2,5-pyrrolidindion 
• 154534-58-4 3-Benzotriazol-1-yl-2,N-dimethyl-4-phenyl-butyramide 
• 110613-39-3 N--L-phenylalanyl-L-alanyl>-5(S)-amino-6-cyclohexyl-4(S)-hydroxy-2-(N-isopentylcarbamoyl)hex-1-ene 
• 110613-55-3 N--L-phenylalanyl-L-alanyl>-5(S)-amino-6-cyclohexyl-4(S)-hydroxy-2-(N-isopentylcarbamoyl)hex-1-ene 1,2-oxide 
• 110613-50-8 (4S,5S)-6-Cyclohexyl-5-[(S)-2-[(S)-2-(3,3-dimethyl-butyrylamino)-3-phenyl-propionylamino]-3-(1H-imidazol-4-yl)-propionylamino]-4-hydroxy-2-methylene-hexanoic acid methylamide 
• 111875-40-2 1,3-dimethyl-5-phenyl-6-oxa-3-azabicyclo<3.1.1>heptane-2,4-dione 
• 74844-32-9 4-Hydroxy-N-methyl-2-methylene-4,4-diphenyl-butyramide 
• 1309763-09-4 1,3-dimethyl-5,6-diphenylpyridin-2(1H)-one 

Relevant articles and documents

Effect of Transition Metals on Chemodivergent Cross-Coupling of Acrylamides with Vinyl Acetate via C-H Activation

A novel chemodivergent cross-coupling of acrylamides and vinyl acetates has been realized via metal-catalyzed vinylic C-H activation. The selective olefinic C-H vinylation and alkenylation reaction was examined with a variety of differently functionalized acrylamides. The reaction efficiently generates a range of highly synthetically valuable butadienes with good functional group tolerance in good to moderate yields. A possible catalytic reaction mechanism involving the chelation-assisted olefinic C-H activation via an acetate-assisted deprotonation pathway is proposed.

PROCESS FOR PREPARING N-METHYL(METH)ACRYLAMIDE

The invention relates to a process for preparing N-methyl(meth)acrylamide and to the uses thereof.

Cobalt-Catalyzed Olefinic C-H Alkenylation/Alkylation Switched by Carbonyl Groups

The first cobalt-catalyzed cross-couplings between olefins has been demonstrated to provide C(alkenyl)-H alkenylation and alkylation products, using complex [Cp?Co(CO)I2]. While coupling partner acrylates afforded conjugated dienoates, α,β-unsaturated ketones led to γ-alkenyl ketones completely, representing a switchable C-H functionalization controlled by different carbonyl groups.