38873-91-5

Basic information

• Product Name: Phenylphosphonic acid bis(p-nitrophenyl) ester
• Synonyms: Phenylphosphonic acid bis(p-nitrophenyl);Phenylphosphonic acid bis(p-nitrophenyl) ester
• CAS NO: 38873-91-5
• Molecular Formula: C₁₈H₁₃N₂O₇P
• Molecular Weight: 400.2788
• Mol File: 38873-91-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 568.6°Cat760mmHg
• Flash Point: 297.7°C
• Appearance: /
• Density: 1.47g/cm³
• Vapor Pressure: 2.34E-12mmHg at 25°C
• Refractive Index: 1.647
• CAS DataBase Reference: Phenylphosphonic acid bis(p-nitrophenyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phenylphosphonic acid bis(p-nitrophenyl) ester(38873-91-5)
• EPA Substance Registry System: Phenylphosphonic acid bis(p-nitrophenyl) ester(38873-91-5)

Safety Data

• Hazardous Substances Data: 38873-91-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C18H13N2O7P/c21-19(22)14-6-10-16(11-7-14)26-28(25,18-4-2-1-3-5-18)27-17-12-8-15(9-13-17)20(23)24/h1-13H

Upstream product

• 824-72-6 P,P-dichlorophenylphosphine oxide 
• 100-02-7 4-nitro-phenol 

Downstream Products

• 20858-29-1 phenyl-phosphonic acid bis-(4-chloro-phenyl ester) 
• 128176-64-7 bis(4-methoxyphenyl) phenylphosphonate 
• 3049-24-9 diphenyl phenylphosphonate 
• 14609-74-6 p-nitrophenolate 

Relevant articles and documents

Direct18F-Labeling of Biomolecules via Spontaneous Site-Specific Nucleophilic Substitution by F-on Phosphonate Prostheses

We describe a high radiochemical yield late-stage direct 18F-labeling of bare biomolecules containing common active groups. Spontaneity and site-selectivity are attributed to the remarkably higher rates of nucleophilic substitution reactions on phosphonates than on other electrophiles by F- at various hydrogen bond forms. Rapid access to many medicinally significant 18F-labeled biomolecules is achieved at 21-68% radiochemical yields and 35.9-55.1 GBq μmol-1 molar activities both manually or automatically.