38968-76-2

Basic information

• Product Name: 2-(4-CHLOROBENZOYL)CYCLOHEXANONE
• Synonyms: 2-(4-CHLOROBENZOYL)CYCLOHEXANONE
• CAS NO: 38968-76-2
• Molecular Formula: C₁₃H₁₃ClO₂
• Molecular Weight: 236.69
• Product Categories: Miscellaneous
• Mol File: 38968-76-2.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(4-CHLOROBENZOYL)CYCLOHEXANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-CHLOROBENZOYL)CYCLOHEXANONE(38968-76-2)
• EPA Substance Registry System: 2-(4-CHLOROBENZOYL)CYCLOHEXANONE(38968-76-2)

Safety Data

• Hazardous Substances Data: 38968-76-2(Hazardous Substances Data)

Usage

General Description

2-(4-Chlorobenzoyl)cyclohexanone is a chemical compound with the molecular formula C13H13ClO2. It is a ketone derivative that is commonly used in organic synthesis and pharmaceutical research. 2-(4-CHLOROBENZOYL)CYCLOHEXANONE is a white to off-white solid that is insoluble in water but soluble in organic solvents. It is typically used as a building block in the synthesis of various pharmaceuticals and agrochemicals. Additionally, it has been found to exhibit antitumor and antimicrobial properties, making it a subject of interest for potential medical applications.

Upstream product

• 108-94-1 cyclohexanone 
• 122-01-0 4-chloro-benzoyl chloride 
• 74-11-3 para-chlorobenzoic acid 
• 13161-16-5 2-[(4-Chloro-phenyl)-hydroxy-methyl]-cyclohexanone 
• 930-68-7 cyclohexenone 
• 873-76-7 para-Chlorobenzyl alcohol 

Downstream Products

• 61054-28-2 3-(4-chlorophenyl)-4,5,6,7-tetrahydrobenzisoxazole 
• 42427-55-4 2-bromo-6-(4-chloro-benzoyl)-cyclohexanone 
• 53661-30-6 1-(4-chlorophenyl)-3-hydroxy-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile 
• 53661-36-2 3-chloro-1-(4-chlorophenyl)-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile 
• 144296-23-1 5-(4-chlorophenyl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c]isoquinolin-1-amine 

Relevant articles and documents

Iridium-catalyzed reaction of enones with alcohols affording 1,3-diketones

An iridium-catalyzed coupling reaction of alcohols with enones has been successfully developed providing access to 1,3-diketones with high selectivity in good yields. This reaction provides an atom-economical route to 1,3-diketones from readily available

Fragment based lead discovery of small molecule inhibitors for the EPHA4 receptor tyrosine kinase

The in silico identification, optimization and crystallographic characterization of a 6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c]isoquinolin-1-amine scaffold as an inhibitor for the EPHA4 receptor tyrosine kinase is described. A database containing commercially

1,3-Diarylcycloalkanopyrazoles and diphenyl hydrazides as selective inhibitors of cyclooxygenase-2

Novel 1,3-diarylcycloalkanopyrazoles 1, and diphenyl hydrazides 2 were identified as selective inhibitors of cyclooxygenase-2. The 1,3-diaryl substitution pattern of the pyrazole ring in 1 differentiates these compounds from most of the known selective COX-2 inhibitors that contain two aryl rings at the adjacent positions on a heterocyclic or a phenyl ring. Similarly, the two phenyl rings in 2 are also separated by three atoms. SAR of both phenyl rings in 1 and 2, and the aliphatic ring in 1 will be discussed. (C) 2000 Elsevier Science Ltd. All rights reserved.