38996-04-2 Usage
Description
[R,(-)]-3-Hydroxy-4-pentenoic acid is a chiral organic compound characterized by the molecular formula C5H8O3. It is a hydroxy acid that features a double bond at the 4-position and a hydroxyl group at the 3-position. [R,(-)]-3-Hydroxy-4-pentenoic acid is recognized for its role as an intermediate in the biosynthesis of various natural products, such as the antibiotic pyoluteorin. Furthermore, it serves as a starting material in the synthesis of numerous pharmaceuticals and biologically active compounds. [R,(-)]-3-Hydroxy-4-pentenoic acid also demonstrates antioxidant properties and has been investigated for its potential health benefits and industrial applications, making it a versatile and significant compound in the realm of organic synthesis.
Uses
Used in Pharmaceutical Synthesis:
[R,(-)]-3-Hydroxy-4-pentenoic acid is used as a starting material for the synthesis of various pharmaceuticals and biologically active compounds. Its unique structure and functional groups make it a valuable building block in the development of new drugs and therapeutic agents.
Used in Natural Product Synthesis:
In the field of natural product synthesis, [R,(-)]-3-Hydroxy-4-pentenoic acid is utilized as an intermediate in the biosynthesis of several natural products, including the antibiotic pyoluteorin. This application highlights its importance in the production of compounds with potential medicinal properties.
Used in Antioxidant Applications:
Due to its antioxidant activity, [R,(-)]-3-Hydroxy-4-pentenoic acid is studied for its potential health benefits. It may be used in the development of supplements or functional foods that promote overall health and well-being by combating oxidative stress.
Used in Industrial Applications:
[R,(-)]-3-Hydroxy-4-pentenoic acid's potential industrial applications are being explored, as its unique properties may be harnessed in various industries, such as the chemical, cosmetic, and food industries, for the development of innovative products and processes.
Check Digit Verification of cas no
The CAS Registry Mumber 38996-04-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,9,9 and 6 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 38996-04:
(7*3)+(6*8)+(5*9)+(4*9)+(3*6)+(2*0)+(1*4)=172
172 % 10 = 2
So 38996-04-2 is a valid CAS Registry Number.
38996-04-2Relevant articles and documents
Substrate evaluation of rhodococcus erythropolis SET1, a nitrile hydrolysing bacterium, demonstrating dual activity strongly dependent on nitrile sub-structure
Coady, Tracey M.,Coffey, Lee V.,O'Reilly, Catherine,Lennon, Claire M.
supporting information, p. 1108 - 1116 (2015/02/19)
Assessment of Rhodococcus erythropolis SET1, a novel nitrile hydrolysing bacterial isolate, has been undertaken with 34 nitriles, 33 chiral and 1 prochiral. These substrates consist primarily of β-hydroxy nitriles with varying alkyl and aryl groups at the β position and containing in several compounds different substituents α to the nitrile. In the case of β-hydroxy nitriles without substitution at the α position, acids were the major products obtained, along with recovered nitrile after biotransformation, as a result of suspected nitrilase activity of the isolate. Unexpectedly, amides were found to be the major hydrolysis product when the β-hydroxy nitriles possessed a vinyl group at this position. To probe this behaviour further, additional related substrates were evaluated containing electron-withdrawing groups at the α position, and amide was also observed upon biotransformation in the presence of SET1. Therefore this novel isolate has also demonstrated NHase activity with nitriles that appears to be substrate-dependent.
A New Approach for the Chemoselective Debromination of Chiral Bromohydrins. Toward the Development of a Very General Approach to Enantiopure α-Unsubstituted β-Hydroxy Acids
Wang, Ying-Chuan,Yan, Tu-Hsin
, p. 6752 - 6755 (2007/10/03)
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