38997-10-3 Usage
Description
(-)-N2'-Deacetyl-N2'-(2-methyl-1-oxopropyl)maytansine is a chemical compound that belongs to the maytansinoid class of toxins, derived from the plant Maytenus ovatus. It is a potent antimitotic agent and microtubule inhibitor, disrupting the formation and function of microtubules in cells, leading to cell cycle arrest and apoptosis.
Uses
Used in Targeted Cancer Therapy:
(-)-N2'-Deacetyl-N2'-(2-methyl-1-oxopropyl)maytansine is used as a potent cytotoxic agent in the development of antibody-drug conjugates for targeted cancer therapy. It can be conjugated to antibodies that specifically target cancer cells, delivering the cytotoxic maytansinoid directly to the tumor cells and minimizing damage to healthy cells.
Used in Pharmaceutical Industry:
(-)-N2'-Deacetyl-N2'-(2-methyl-1-oxopropyl)maytansine is being studied for its efficacy in treating various types of cancer, including breast, lung, and ovarian cancers. Its targeted delivery system and potent antimitotic properties make it a promising candidate for cancer treatment in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 38997-10-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,9,9 and 7 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 38997-10:
(7*3)+(6*8)+(5*9)+(4*9)+(3*7)+(2*1)+(1*0)=173
173 % 10 = 3
So 38997-10-3 is a valid CAS Registry Number.
InChI:InChI=1/C36H50ClN3O10/c1-19(2)32(42)39(7)22(5)33(43)49-28-17-29(41)40(8)24-15-23(16-25(46-9)30(24)37)14-20(3)12-11-13-27(47-10)36(45)18-26(48-34(44)38-36)21(4)31-35(28,6)50-31/h11-13,15-16,19,21-22,26-28,31,45H,14,17-18H2,1-10H3,(H,38,44)/b13-11+,20-12-
