3907-02-6

Basic information

• Product Name: 2-AMino-3,3-diMethyl-1-butanol
• Synonyms: 2-amino-3,3-dimethylbutan-1-ol(WXC08520)
• CAS NO: 3907-02-6
• Molecular Formula: C₆H₁₅NO
• Molecular Weight: 117.1894
• Mol File: 3907-02-6.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 198.5±13.0 °C(Predicted)
• Appearance: /
• Density: 0.907±0.06 g/cm3(Predicted)
• PKA: 12.88±0.10(Predicted)
• CAS DataBase Reference: 2-AMino-3,3-diMethyl-1-butanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMino-3,3-diMethyl-1-butanol(3907-02-6)
• EPA Substance Registry System: 2-AMino-3,3-diMethyl-1-butanol(3907-02-6)

Safety Data

• Hazardous Substances Data: 3907-02-6(Hazardous Substances Data)

Usage

Description

2-Amino-3,3-dimethyl-1-butanol, a chemical compound with the molecular formula C6H15NO, is an aminoalcohol characterized by the presence of both amine and alcohol functional groups. This colorless liquid exhibits a faint, ammonia-like odor and is known for its chelating, corrosion-inhibiting, and surfactant properties, making it a versatile compound in various industrial applications.

Uses

Used in Metalworking Fluids:
2-Amino-3,3-dimethyl-1-butanol is used as a chelating agent and corrosion inhibitor in metalworking fluids, enhancing the performance and longevity of these fluids by preventing metal corrosion and improving their stability.
Used in Oilfield Chemicals:
In the oil and gas industry, 2-Amino-3,3-dimethyl-1-butanol serves as a chelating agent and corrosion inhibitor, ensuring the efficient extraction and processing of oil by preventing equipment corrosion and maintaining the stability of drilling fluids.
Used in Water Treatment Compounds:
2-Amino-3,3-dimethyl-1-butanol is utilized as a chelating agent in water treatment processes, helping to remove impurities and contaminants by binding with metal ions, thus improving water quality and safety.
Used in Pharmaceutical Synthesis:
2-AMino-3,3-diMethyl-1-butanol is employed as an intermediate in the synthesis of various pharmaceuticals, contributing to the development of new drugs and medications.
Used in Agrochemical Production:
2-Amino-3,3-dimethyl-1-butanol is used in the production of agrochemicals, such as pesticides and fertilizers, where it acts as a building block for the synthesis of active ingredients.
Used in Surfactant Production:
Due to its surfactant properties, 2-Amino-3,3-dimethyl-1-butanol is used in the manufacturing of surfactants, which are essential components in cleaning and detergent products.
Used in Detergent Formulation:
2-AMino-3,3-diMethyl-1-butanol is used as a foam stabilizer and emulsifier in detergent formulations, enhancing the cleaning performance and improving the texture and stability of detergent products.
Used in Personal Care Products:
2-Amino-3,3-dimethyl-1-butanol is utilized in the production of personal care products, such as shampoos, soaps, and lotions, where it acts as a foam stabilizer and emulsifier, ensuring product efficacy and improving user experience.

Upstream product

• 112245-08-6 methyl (R)-2-amino-3,3-dimethylbutanoate 
• 167223-43-0 L-tert-butylglycine methyl ester hydrochloride 
• 43165-46-4 sodium 3,3-dimethyl-2-oxobutyrate 
• 393536-67-9 (R)-1-(benzyloxymethyl)-2,2-dimethylpropylamine 
• 393536-38-4 (R_S,1R)-2-methylpropane-2-sulfinic acid [1-((tert-butyldimethylsilanyloxy)methyl)-2,2-dimethylpropyl]amide 
• 26782-71-8 D-tert-leucine 
• 393536-30-6 (R_S,1R)-2-methylpropane-2-sulfinic acid (1-(benzyloxymethyl)-2,2-dimethylpropyl)amide 
• 62965-34-8 Trimethylpyruvic acid oxime 

Downstream Products

• 93684-48-1 4,5-dihydro-4-(1,1-dimethylethyl)-2-(2-methyl-2-phenylpropyl)oxazole 
• 93684-45-8 4,5-dihydro-4-(1,1-dimethylethyl)-2-(2-phenylethyl)oxazole 
• 219321-13-8 5-benzoyl-3-tert-butyl-8a-hydroxy-3,4-dihydro-2H,8aH-benzo[1,4]oxazin-8-one 
• 93684-60-7 4,5-dihydro-4-(1,1-dimethylethyl)-2-ethyl-3-(2-propenyl)oxazolinium 4-methylbenzenesulfonate 
• 93684-56-1 4,5-dihydro-4-(1,1-dimethylethyl)-2-(2-phenylethyl)-3-(2-propenyl)oxazolinium 4-methylbenzenesulfonate 
• 93684-62-9 4,5-dihydro-4-(1,1-dimethylethyl)-2-(2-methyl-2-phenylpropyl)-3-(2-propenyl)oxazolinium 4-methylbenzenesulfonate 
• 170970-21-5 2-t-butyl-1-(p-tolylsulphonyl)aziridine 
• 1357170-63-8 2‐(tert‐butyl)‐5‐phenyl‐1H‐pyrrole 
• 226387-12-8 C₁₆H₁₈N₂O 

Relevant articles and documents

Total Synthesis of the Alleged Structure of Crenarchaeol Enables Structure Revision**

Crenarchaeol is a glycerol dialkyl glycerol tetraether lipid produced exclusively in Archaea of the phylum Thaumarchaeota. This membrane-spanning lipid is undoubtedly the structurally most sophisticated of all known archaeal lipids and an iconic molecule in organic geochemistry. The 66-membered macrocycle possesses a unique chemical structure featuring 22 mostly remote stereocenters, and a cyclohexane ring connected by a single bond to a cyclopentane ring. Herein we report the first total synthesis of the proposed structure of crenarchaeol. Comparison with natural crenarchaeol allowed us to propose a revised structure of crenarchaeol, wherein one of the 22 stereocenters is inverted.

Synthesis and Cytotoxicity Evaluation of C4- and C5-Modified Analogues of the α,β-Unsaturated Lactone of Pironetin

Pironetin is a natural product with potent antiproliferative activity that forms a covalent adduct with α-tubulin via conjugate addition into the natural product's α,β-unsaturated lactone. Although pironetin's α,β-unsaturated lactone is involved in its binding to tubulin, the structure–activity relationship at different positions of the lactone have not been thoroughly evaluated. For a systematic evaluation of the structure–activity relationships at the C4 and C5 positions of the α,β-unsaturated lactone of pironetin, twelve analogues of the natural product were prepared by total synthesis. Modifying the stereochemistry at the C4 and/or C5 positions of the α,β-unsaturated lactone of pironetin resulted in loss of antiproliferative activity in OVCAR5 ovarian cancer cells. While changing the C4 ethyl substituent with groups such as methyl, propyl, cyclopropyl, and isobutyl were tolerated, groups with larger steric properties such as an isopropyl and benzyl groups were not.

Chiral auxiliaries as docking/protecting groups in biohydroxylation: (S)-specific hydroxylation of enantiopure tert-butyl-substituted spirooxazolidines derived from cyclopentanone

An enantiopure tert-butyl-substituted derivative of cyclopentanone, which is a vital member of the chiral docking/ protecting group series, is employed, for the first time, to stereoselectively (90% de) introduce an (S)-configured hydroxyl group onto an unactivated carbon atom present in the cyclopentane ring using the fungus Beauveria bassiana ATCC 7159. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005.