39124-16-8Relevant articles and documents
Extended diethylglycine homopeptides formed by desulfurization of their tetrahydrothiopyran analogues
De Zotti, Marta,Clayden, Jonathan
supporting information, p. 2209 - 2212 (2019/04/10)
Diethylglycine (Deg) homopeptides adopt the rare 2.05-helical conformation, the longest three-dimensional structure that a peptide of a given sequence can adopt. Despite this unique conformational feature, Deg is rarely used in peptide design b
Method for the synthesis of compounds of formula 1 and derivatives thereof
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Page 13, (2008/06/13)
Mono-substituted and di-substituted alpha-amino acids and derivatives thereof, substituted at the alpha positon with one (mono-) or two (di-) substituents (R2 and/or R3) as shown in Formula 1: N(R4R5)C(R2R3)CO(OR1).
ARYLSUFONAMIDO-SUBSTITUTED HYDROXAMIC ACIDS
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, (2008/06/13)
The invention relates to a method of inhibiting metalloellastase activity, of inhibiting the degradation of elastin, or of treating macrophage metalloelastase dependent conditions in mammals which comprises administering to a mammal in need thereof an effective macrophage metalloelastase inhibiting amount of a compound of formula I STR1 wherein Ar, R, R 1 and R. sub.2 have meanings as defined, or of a pharmaceutically acceptable prodrug derivative thereof, or of a pharmaceutically acceptable salt thereof, or of pharmaceutical compositions comprising a said compound.