39133-31-8 Usage
Description
3,4,5-Trimethoxybenzoic acid 2-(dimethylamino)-2-phenylbutyl ester is a complex organic compound characterized by its unique chemical structure, which features a benzoic acid core with three methoxy groups at positions 3, 4, and 5. Additionally, it has a dimethylamino group and a 2-phenylbutyl ester group attached to it. This molecule is known for its potential applications in various industries due to its specific properties and interactions with biological systems.
Uses
Used in Pharmaceutical Industry:
3,4,5-Trimethoxybenzoic acid 2-(dimethylamino)-2-phenylbutyl ester is used as an active pharmaceutical ingredient for the development of drugs targeting the peripheral mu, kappa, and delta opiate receptors. Its agonistic activity on these receptors makes it a potent spasmolytic agent, effective in treating both acute and chronic abdominal pain. 3,4,5-Trimethoxybenzoic acid 2-(dimethylamino)-2-phenylbutyl ester's ability to alleviate pain and reduce muscle spasms in the gastrointestinal tract is attributed to its interaction with the opioid receptors, leading to a decrease in gut motility and pain perception.
Used in Drug Delivery Systems:
In the field of drug delivery, 3,4,5-Trimethoxybenzoic acid 2-(dimethylamino)-2-phenylbutyl ester can be utilized as a component in the design of novel drug delivery systems. Its unique chemical structure and properties may allow for the development of targeted drug carriers, enhancing the bioavailability and therapeutic outcomes of various medications. By incorporating this compound into drug delivery systems, researchers can potentially improve the efficacy and safety of drugs, particularly for the treatment of gastrointestinal disorders and pain management.
Used in Chemical Research:
3,4,5-Trimethoxybenzoic acid 2-(dimethylamino)-2-phenylbutyl ester can also be employed as a research tool in the field of chemical biology. Its specific interactions with biological systems and unique chemical properties make it a valuable compound for studying receptor binding, signal transduction pathways, and other cellular processes. Researchers can use this molecule to gain insights into the mechanisms of action of various drugs and to develop new therapeutic strategies for a range of medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 39133-31-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,1,3 and 3 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 39133-31:
(7*3)+(6*9)+(5*1)+(4*3)+(3*3)+(2*3)+(1*1)=108
108 % 10 = 8
So 39133-31-8 is a valid CAS Registry Number.
InChI:InChI=1/C22H29NO5/c1-7-22(23(2)3,17-11-9-8-10-12-17)15-28-21(24)16-13-18(25-4)20(27-6)19(14-16)26-5/h8-14H,7,15H2,1-6H3
39133-31-8Relevant articles and documents
Direct Conversion of N-Alkylamines to N-Propargylamines through C-H Activation Promoted by Lewis Acid/Organocopper Catalysis: Application to Late-Stage Functionalization of Bioactive Molecules
Chan, Jessica Z.,Yesilcimen, Ahmet,Cao, Min,Zhang, Yuyang,Zhang, Bochao,Wasa, Masayuki
supporting information, p. 16493 - 16505 (2020/10/26)
An efficient catalytic method to convert an α-C-H bond of N-alkylamines into an α-C-alkynyl bond was developed. In the past, such transformations were carried out under oxidative conditions, and the enantioselective variants were confined to tetrahydroisoquinoline derivatives. Here, we disclose a method for the union of N-alkylamines and trimethylsilyl alkynes, without the presence of an external oxidant and promoted through cooperative actions of two Lewis acids, B(C6F5)3 and a Cu-based complex. A variety of propargylamines can be synthesized in high diastereo-and enantioselectivity. The utility of the approach is demonstrated by the late-stage site-selective modification of bioactive amines. Kinetic investigations that shed light on various mechanistic nuances of the catalytic process are presented.
