39136-61-3

Basic information

• Product Name: 5-Propylthiazol-2-amine
• Synonyms: 5-Propylthiazol-2-amine;4-Propyl-thiazol-2-ylamine;5-propylthiazol-2ylamine
• CAS NO: 39136-61-3
• Molecular Formula: C₆H₁₀N₂S
• Molecular Weight: 142.222
• Mol File: 39136-61-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-Propylthiazol-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Propylthiazol-2-amine(39136-61-3)
• EPA Substance Registry System: 5-Propylthiazol-2-amine(39136-61-3)

Safety Data

• Hazardous Substances Data: 39136-61-3(Hazardous Substances Data)

Usage

General Description

5-Propylthiazol-2-amine is a chemical compound classified under the category of organosulfur and organonitrogen compounds, specifically a part of the thiazoles subgroup. It's a derivative of thiazole, which is a heterocyclic compound with a ring structure composed of three carbon atoms, one nitrogen atom, and one sulfur atom. As its name denotes, this specific derivative has a propyl (three-carbon) group attached to the thiazole ring. Information regarding its specific applications or uses is not readily accessible, suggesting it may be primarily utilized in research or specialized industrial scenarios. Exact details regarding the compound's properties such as its toxicity, reactivity, or environmental impact are also not widely available.

Upstream product

• 71-41-0 pentan-1-ol 
• 110-62-3 pentanal 
• 17356-08-0 thiourea 
• 35066-19-4 2-bromopentanal 

Downstream Products

• 39122-75-3 Ethyl-N-(5-n-propylthiazol-2-yl)carbamat 
• 39136-60-2 5-ethylthiazol-2-amine 
• 851531-46-9 6-(3,6-dimethoxy-2-nitro-phenyl)-2-propyl-imidazo[2,1-b]thiazole 
• 924883-32-9 6-(2,4-dichloro-5-nitro-phenyl)-2-propyl-imidazo[2,1-b]thiazole 
• 924883-73-8 6-(2,4-dichloro-5-nitro-phenyl)-2-propyl-imidazo[2,1-b]thiazole-5-carbaldehyde 

Relevant articles and documents

NOVEL KINASE INHIBITORS

The present invention provides derivatives of thiazolylamino-substituted heterocycles. These compounds are inhibitors of kinases, including compounds that show antiproliferative activity against cells, including against tumor cells, and are useful in the treatment of diseases including cancer.

6-thienyl and 6-phenylimidazo[2,1-b]thiazoles as inhibitors of mitochondrial NADH dehydrogenase

Starting from the potent inhibitory effect of the previously described 2-methyl-6-(2-thienyl)imidazo[2,1-b]thiazole on mitochondrial complex I, we prepared a series of derivatives in order to study the effect of a different substitution at the positions 2, 5 and 6. The replacement of the thienyl group at position 6 with a phenyl group does not modify the biological behaviour of the lead compound, whereas the shift of the methyl group from position 2 to position 5 yields a compound devoid of inhibitory effects. In both the 6-thienyl and 6-phenyl series, the lengthening of the chain at position 2 has provided useful information to outline the structural determinants of the ubiquinone antagonist action in imidazothiazole derivatives.