3914-44-1

Basic information

• Product Name: 2-(Chloromethyl)-5-methoxy-1,3,4-thiadiazole
• Synonyms: 2-(Chloromethyl)-5-methoxy-1,3,4-thiadiazole
• CAS NO: 3914-44-1
• Molecular Formula: C₄H₅ClN₂OS
• Molecular Weight: 164.6133
• Mol File: 3914-44-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(Chloromethyl)-5-methoxy-1,3,4-thiadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Chloromethyl)-5-methoxy-1,3,4-thiadiazole(3914-44-1)
• EPA Substance Registry System: 2-(Chloromethyl)-5-methoxy-1,3,4-thiadiazole(3914-44-1)

Safety Data

• Hazardous Substances Data: 3914-44-1(Hazardous Substances Data)

Usage

General Description

2-(Chloromethyl)-5-methoxy-1,3,4-thiadiazole is a chemical compound with the molecular formula C4H5ClN2O2S. It is a thiadiazole derivative that contains chlorine and a methoxy group. 2-(Chloromethyl)-5-methoxy-1,3,4-thiadiazole has potential applications in medicinal chemistry, as it can be used as a building block in the synthesis of pharmaceuticals and agrochemicals. Its structure and properties make it a versatile intermediate in the development of various bioactive molecules. Additionally, it has been studied for its potential biological activities and pharmacological properties, which makes it a subject of interest for further research and development in the field of drug discovery.

Upstream product

• 3914-43-0 N'-chloroacetyl-hydrazinecarbothioic acid O-methyl ester 
• 36743-66-5 ethyl chloroacetimidate hydrochloride 
• 19692-07-0 methyl imidothiocarbamate 

Downstream Products

• 38090-82-3 dithiophosphoric acid O,O'-diethyl ester S-(5-methoxy-[1,3,4]thiadiazol-2-ylmethyl) ester 
• 38090-81-2 dithiophosphoric acid S-(5-methoxy-[1,3,4]thiadiazol-2-ylmethyl) ester O,O'-dimethyl ester 
• 38090-84-5 thiophosphoric acid O,O'-diethyl ester S-(5-methoxy-[1,3,4]thiadiazol-2-ylmethyl) ester 

Relevant articles and documents

Synthesis and biological activities of novel 1,3,4-thiadiazole-containing pyrazole oxime derivatives

A new library of 1,3,4-thiadiazole-containing pyrazole oximes was designed and synthesized. Their acaricidal and insecticidal activities were evaluated. Bioassay results indicated that some target compounds exhibited good acaricidal and insecticidal properties. Especially, compound 8m had 80% acaricidal activity against Tetranychus cinnabarinus at the concentration of 50?μg/mL, compound 8f displayed 100% insecticidal activities against Aphis craccivora at the concentration of 50?μg/mL, compounds 8r and 8w showed 100% insecticidal activities against Plutella xylostella at the concentration of 50?μg/mL. Furthermore, compounds 8r (LC50?=?19.61?μg/mL) and 8w (LC50?=?9.78?μg/mL) possessed comparable or even better insecticidal activities than the control Pyridalyl (LC50?=?17.40?μg/mL) against P. xylostella.