39150-37-3

Basic information

• Product Name: 2-CYANO-7-NITROFLUORENE
• Synonyms: 2-CYANO-7-NITROFLUORENE
• CAS NO: 39150-37-3
• Molecular Formula: C14H8 N2 O2
• Molecular Weight: 0
• Mol File: 39150-37-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 439°Cat760mmHg
• Flash Point: 219.3°C
• Appearance: /
• Density: 1.4g/cm³
• Vapor Pressure: 6.62E-08mmHg at 25°C
• Refractive Index: 1.692
• CAS DataBase Reference: 2-CYANO-7-NITROFLUORENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CYANO-7-NITROFLUORENE(39150-37-3)
• EPA Substance Registry System: 2-CYANO-7-NITROFLUORENE(39150-37-3)

Safety Data

• Hazardous Substances Data: 39150-37-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H8N2O2/c15-8-9-1-3-13-10(5-9)6-11-7-12(16(17)18)2-4-14(11)13/h1-5,7H,6H2

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Relevant articles and documents

A new water-soluble near-neutral ratiometric fluorescent pH indicator

Donor-π-acceptor fluorene derivative 1c is a near-neutral pH indicator whose pKa of ～7.0 was determined by both absorption and fluorescence methods. 1c satisfies important criteria for a sensitive ratiomeric fluorescent pH indicator with a distinctive isoemissive point, good dispersion in cell cytosol, and low cytotoxicity. Furthermore, its 2PA cross section of 100 GM in its neutral form suggests its potential in two-photon fluorescence imaging applications.

Two-photon absorbing water soluble fluorescent probe as a near neutral pH indicator

Disclosed are fluorescent compounds useful as intracellular pH probes. In particular, the invention teaches a two-photon absorbing, water soluble, fluorescent compound, a fluorene derivative, which is effective as a near-neutral pH indicator and particularly as an intracellular probe. A method for chemical synthesis of the claimed compounds is provided.