391614-10-1

Basic information

• Product Name: 3-(2-bromobenzylidene)oxindole
• Synonyms: 3-(2-bromobenzylidene)oxindole
• CAS NO: 391614-10-1
• Molecular Weight: 300.154
• Mol File: 391614-10-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-(2-bromobenzylidene)oxindole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-bromobenzylidene)oxindole(391614-10-1)
• EPA Substance Registry System: 3-(2-bromobenzylidene)oxindole(391614-10-1)

Safety Data

• Hazardous Substances Data: 391614-10-1(Hazardous Substances Data)

Upstream product

• 59-48-3 2-oxoindole 
• 6630-33-7 ortho-bromobenzaldehyde 

Downstream Products

• 1185774-33-7 3-(2-bromobenzyl)indolin-2-one 

Relevant articles and documents

Photoredox asymmetric catalytic enantioconvergent substitution of 3-chlorooxindoles

An enantioconvergent substitution of 3-substituted 3-chlorooxindoles with N-aryl glycines under visible light irradiation is reported. A transition-metal-free cooperative catalysis platform with a dicyanopyrazine-derived chromophore (DPZ) as a photoredox catalyst and a chiral Br?nsted acid catalyst is effective for these transformations, which involve a single-electron transfer redox step and an enantioselective radical coupling. A variety of valuable chiral 3-aminomethylene-3-substituted oxindoles can be directly synthesized with high yields and enantioselectivities.

Highly enantioselective and organocatalytic α-amination of 2-Oxindoles

Figur Presented An effective method for the asymmetric synthesis of 3-amino-2-oxindoles was developed. The tetrasubstituted chiral carbon center was generated by asymmetric amination of N-unprotected 2-oxindoles with azodicarboxylate catalyzed by commercial biscinchona alkaloids in good to excellent yields with high enantioselectivities.