39165-01-0

Basic information

• Product Name: N-(3-chlorophenyl)-2-oxo-2-phenylacetamide
• Synonyms: N-(3-chlorophenyl)-2-oxo-2-phenylacetamide
• CAS NO: 39165-01-0
• Molecular Weight: 259.692
• Mol File: 39165-01-0.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: N-(3-chlorophenyl)-2-oxo-2-phenylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-chlorophenyl)-2-oxo-2-phenylacetamide(39165-01-0)
• EPA Substance Registry System: N-(3-chlorophenyl)-2-oxo-2-phenylacetamide(39165-01-0)

Safety Data

• Hazardous Substances Data: 39165-01-0(Hazardous Substances Data)

Upstream product

• 54507-99-2 N-(3-chlorophenyl)cyanamide 
• 611-73-4 Benzoylformic acid 
• 2909-38-8 m-chlorophenyl isocyanate 
• 50625-49-5 m-Chlorobenzoyl azide 
• 25726-04-9 phenylglyoxylyl chloride 
• 108-42-9 3-chloro-aniline 
• 5330-63-2 t-butyl 3-chlorophenylcarbamate 
• 932-87-6 1-Bromo-2-phenylacetylene 
• 103-80-0 phenylacetyl chloride 
• 18109-43-8 N-(3-chlorophenyl)-2-phenylacetamide 

Relevant articles and documents

Rapid assembly of α-ketoamides through a decarboxylative strategy of isocyanates with α-oxocarboxylic acids under mild conditions

A simple and practical method for α-ketoamide synthesis via a decarboxylative strategy of isocyanates with α-oxocarboxylic acids is described. The reaction proceeds at room temperature under mild conditions without an oxidant or an additive, showing good substrate scope and functional compatibility. Moreover, the applicability of this method was further demonstrated by the synthesis of various bioactive molecules and different application examples through a two-step one-pot operation.

Catalyst- and Additive-Free Chemoselective Transfer Hydrogenation of α-Keto Amides to α-Hydroxy Amides by Sodium Formate

A catalyst- and additive-free chemoselective transfer hydrogenation of α-keto amides to α-hydroxy amides is easily achieved by using sodium formate as a hydrogen source. The utility of this method is demonstrated by gram-scale synthesis and transformation of the resultant α-hydroxy amides into polysubstituted acetamides and 2-arylindole derivatives. Control experiments suggest that the NH group of α-keto amides is crucial for the chemoselective reduction through the formation of hydrogen bonds.

Friedel-Crafts Hydroxyalkylation of Indoles with α-Keto Amides using Reusable K3PO4/ nBu4NBr Catalytic System in Water

A mild and operationally simple Friedel-Crafts hydroxyalkylation of indoles with α-keto amides was developed for the first time by using catalytic amount of K3PO4 and nBu4NBr in water as solvent through a solid-liquid inte