391687-99-3Relevant articles and documents
The preparation of chiral salicylaldehydes based on Kagan's ether
Harmata,Wu,Kahraman,Welch
, p. 3345 - 3359 (2007/10/03)
Two related routes to chiral salicylaldehydes which are derivatives of Kagan's ether have been developed. One route which is particularly simple begins with 2,6-diallylphenol. Facile conversion to a substituted benzofuran and assemblage of the basic framework of Kagan's ether is followed by an ozonolysis of the benzofuran ring to reveal the hydroxyaldehyde functionality characteristic of salicylaldehydes.