39190-95-9

Basic information

• Product Name: CHEMBRDG-BB 4024874
• Synonyms: CHEMBRDG-BB 4024874;N-PROPYLCYCLOPENTANAMINE;UKRORGSYN-BB BBV-063287;N-propylcyclopentanamine(SALTDATA: HCl)
• CAS NO: 39190-95-9
• Molecular Formula: C₈H₁₇N
• Molecular Weight: 127.229
• Mol File: 39190-95-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 168.9°C at 760 mmHg
• Flash Point: 43.5°C
• Appearance: /
• Density: 0.84g/cm³
• Vapor Pressure: 1.58mmHg at 25°C
• Refractive Index: 1.452
• CAS DataBase Reference: CHEMBRDG-BB 4024874(CAS DataBase Reference)
• NIST Chemistry Reference: CHEMBRDG-BB 4024874(39190-95-9)
• EPA Substance Registry System: CHEMBRDG-BB 4024874(39190-95-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 39190-95-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H17N/c1-2-7-9-8-5-3-4-6-8/h8-9H,2-7H2,1H3

Upstream product

• 10442-97-4 cyclopentanone oxime tosylate 
• 102-67-0 tri-n-propylaluminum 
• 107-10-8 propylamine 
• 120-92-3 cyclopentanone 
• 1192-28-5 Cyclopentanone oxime 

Downstream Products

• 207851-42-1 N-cyclopentyl-N-propylformamide 

Relevant articles and documents

IDO INHIBITORS

There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or autoimmune diseases utilizing the compounds of the invention.

Organoaluminum-Promoted Beckmann Rearrangement of Oxime Sulfonates

The Beckmann rearrangement of oxime sulfonates with simultaneous nucleophilic trapping of the intermediary iminocarbocation by organoaluminum reagents is described.This process provides a new and highly efficient route to imino thioethers, imino selenoethers, imino nitriles, and α-alkylated amines starting from oxime sulfonates by the use of dialkylaluminum thiolates, selenolates, diethylaluminum chloride-trimethylsilyl cyanide, and trialkylaluminum-diisobutylaluminum hydride systems, respectively.The present organoaluminum-promoted Beckmann rearrangement of oxime sulfonates has been successfully applied to the synthesis of naturally occuring alkaloids, pumiliotoxin C and solenopsin A and B, in stereoselective fashion.Moreover, α,α-dialkylation of amines can be realized by the successive treatment of oxime sulfonates with trialkylaluminum followed by allylic or propargylic Grignard reagents in synthetically useful yields.