391906-88-0Relevant articles and documents
Novel (4-piperidin-1-yl)-phenyl sulfonamides as potent and selective human β3 agonists
Hu, Baihua,Ellingboe, John,Han, Stella,Largis, Elwood,Lim, Kitae,Malamas, Michael,Mulvey, Ruth,Niu, Chuansheng,Oliphant, Alexander,Pelletier, Jeffrey,Singanallore, Thiruvikraman,Sum, Fuk-Wah,Tillett, Jeff,Wong, Victoria
, p. 2045 - 2059 (2007/10/03)
A series of novel (4-piperidin-1-yl)-phenyl sulfonamides was prepared and evaluated for their biological activity on the human β3-adrenergic receptor (AR). Replacement of the 3,4-dihydroxyl group of the catechol moiety with 4-hydroxyl-3-methyl