39235-92-2Relevant articles and documents
Novel benzimidazole-triazole hybrids as apoptosis inducing agents in lung cancer: Design, synthesis, 18F-radiolabeling & galectin-1 inhibition studies
Sridhar Goud, Nerella,Pooladanda, Venkatesh,Muni Chandra,Lakshmi Soukya,Alvala, Ravi,Kumar, Pardeep,Nagaraj, Chandana,Dawn Bharath, Rose,Qureshi, Insaf A.,Godugu, Chandraiah,Alvala, Mallika
, (2020/07/31)
In this study, we have synthesized a new series of benzimidazole-triazole hybrids as galectin-1 (gal-1) mediated apoptosis-inducing agents, and evaluated for their potential anticancer activity against a panel of human cancer cell lines viz. breast cancer
Synthesis of 1-benzyl-1H-benzimidazoles as galectin-1 mediated anticancer agents
Goud, Nerella Sridhar,Ghouse, S. Mahammad,Vishnu, Jatoth,Komal,Talla, Venu,Alvala, Ravi,Pranay, Jakkula,Kumar, Janish,Qureshi, Insaf A.,Alvala, Mallika
, (2019/06/13)
In our pursuit to develop novel non-carbohydrate small molecule Galectin-1 Inhibitors, we have designed a series of 1-benzyl-1H-benzimidazole derivatives and demonstrated their anticancer activity. The compound 6g, 4-(1-benzyl-5-chloro-1H-benzo[d]imidazol
Synthesis of substituted phenanthrene-9-benzimidazole conjugates: Cytotoxicity evaluation and apoptosis inducing studies
Kumar, Niggula Praveen,Sharma, Pankaj,Kumari, S. Sujana,Brahma, Umarani,Nekkanti, Shalini,Shankaraiah, Nagula,Kamal, Ahmed
, p. 128 - 140 (2017/09/20)
A series of new phenanthrene-9-benzimidazole conjugates has been synthesized by condensing phenanthrene aldehydes with various substituted o-phenylenediamines. The title compounds were evaluated for their in vitro cytotoxic potential against various human