39251-86-0

Basic information

• Product Name: FEMA 2571
• Synonyms: N-HEXYL FUROATE;2-furancarboxylicacid,hexylester;furan-2-carboxylicacidhexylester;HEXYL 2-FUROATE;HEXYL FUROATE;FEMA 2571;HEXYL 2-FUROATE 97+%
• CAS NO: 39251-86-0
• Molecular Formula: C₁₁H₁₆O₃
• Molecular Weight: 196.24
• EINECS: 254-377-3
• Mol File: 39251-86-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 105 °C1 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.017 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.00776mmHg at 25°C
• Refractive Index: n20/D 1.472(lit.)
• CAS DataBase Reference: FEMA 2571(CAS DataBase Reference)
• NIST Chemistry Reference: FEMA 2571(39251-86-0)
• EPA Substance Registry System: FEMA 2571(39251-86-0)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 39251-86-0(Hazardous Substances Data)

Usage

Description

FEMA 2571, also known as Hexyl 2-furoate, is a synthetic compound characterized by its unique chemical properties and distinct sensory characteristics. It possesses a peculiar, fruity, earthy, yet sweet and pear-like odor, with a taste threshold value that contributes to its various applications in different industries.

Uses

Used in Flavor and Fragrance Industry:
FEMA 2571 is used as a flavoring agent for its green, waxy, fruity pear, and apple notes at 20 ppm. Its unique taste and aroma make it a valuable addition to the flavor and fragrance industry, enhancing the sensory experience of various products.
Used in the Cosmetic Industry:
FEMA 2571 is used as a fragrance ingredient in the cosmetic industry, where its distinctive scent can be utilized in the formulation of perfumes, lotions, and other personal care products. Its green, wine-like, and musty characteristics provide a unique and appealing sensory profile for consumers.
Used in the Food and Beverage Industry:
FEMA 2571 is used as an additive in the food and beverage industry to impart its characteristic flavor and aroma to a variety of products. Its fruity and earthy notes can be used to enhance the taste of beverages, confectioneries, and other food items, providing a unique and enjoyable sensory experience for consumers.

InChI:InChI=1/C11H16O3/c1-2-3-4-5-8-14-11(12)10-7-6-9-13-10/h6-7,9H,2-5,8H2,1H3

Upstream product

• 88-14-2 2-furanoic acid 
• 111-27-3 hexan-1-ol 
• 693-02-7 hex-1-yne 
• 527-69-5 2-furancarbonyl chloride 

Downstream Products

• 4282-32-0 furan-2,5-dicarboxylic acid dimethyl ester 

Relevant articles and documents

Mild olefin formationviabio-inspired vitamin B12photocatalysis

Dehydrohalogenation, or elimination of hydrogen-halide equivalents, remains one of the simplest methods for the installation of the biologically-important olefin functionality. However, this transformation often requires harsh, strongly-basic conditions, rare noble metals, or both, limiting its applicability in the synthesis of complex molecules. Nature has pursued a complementary approach in the novel vitamin B12-dependent photoreceptor CarH, where photolysis of a cobalt-carbon bond leads to selective olefin formation under mild, physiologically-relevant conditions. Herein we report a light-driven B12-based catalytic system that leverages this reactivity to convert alkyl electrophiles to olefins under incredibly mild conditions using only earth abundant elements. Further, this process exhibits a high level of regioselectivity, producing terminal olefins in moderate to excellent yield and exceptional selectivity. Finally, we are able to access a hitherto-unknown transformation, remote elimination, using two cobalt catalysts in tandem to produce subterminal olefins with excellent regioselectivity. Together, we show vitamin B12to be a powerful platform for developing mild olefin-forming reactions.

Direct Alkoxycarbonylation of Heteroarenes via Cu-Mediated Trichloromethylation and in Situ Alcoholysis

We report an efficient approach for direct alkoxycarbonylation of furans as well as other heteroarenes via a one-step copper-mediated reaction of three components (i.e., heteroarene, alcohol, and CHCl3). The copper additive was confirmed to simultaneously promote the reaction in three pathways: oxidant cracking, single electron transfer, and alcoholysis. By means of this protocol, various functionalized furancarboxylates and other heteroarenecarboxylates were facilely obtained in moderate to good yields.

Cesium Carbonate Catalyzed Esterification of N-Benzyl- N-Boc-amides under Ambient Conditions

We report a general activated amide to ester transformation catalyzed by Cs2CO3. Using this approach, esterification proceeds under relatively mild conditions and without the need for a transition metal catalyst. This method exhibits broad substrate scope and represents a practical alternative to existing esterification strategies. The synthetic utility of this protocol is demonstrated via the facile synthesis of crown ether derivatives and the late-stage modification of a representative natural product and several sugars in reasonable yields.