39255-23-7

Basic information

• Product Name: 1-bromo-4-(2-methoxyethoxy)benzene
• Synonyms: 1-bromo-4-(2-methoxyethoxy)benzene;4-(2-Methoxyethoxy)-1-bromobenzene;4-(2-Methoxyethoxy)bromobenzene
• CAS NO: 39255-23-7
• Molecular Formula: C₉H₁₁BrO₂
• Molecular Weight: 231.08644
• Mol File: 39255-23-7.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-bromo-4-(2-methoxyethoxy)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-bromo-4-(2-methoxyethoxy)benzene(39255-23-7)
• EPA Substance Registry System: 1-bromo-4-(2-methoxyethoxy)benzene(39255-23-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 39255-23-7(Hazardous Substances Data)

Usage

General Description

1-bromo-4-(2-methoxyethoxy)benzene, also known as bromoanisole, is an organic compound primarily used as a building block in organic synthesis and pharmaceutical manufacturing. It consists of a benzene ring with a bromine atom at the 1 position and an attached 2-methoxyethoxy group at the 4 position. This chemical is commonly utilized as a reagent in the production of various pharmaceuticals, agrochemicals, and other fine chemicals. It is also used in the synthesis of liquid crystals and other organic compounds. Additionally, bromoanisole is known for its pleasant and exotic aroma, making it a valuable ingredient in the fragrance industry. However, it is important to handle this chemical with caution due to its potential hazards and toxicity.

Upstream product

• 41532-81-4 2-methoxyethyl phenyl ether 
• 106-41-2 4-bromo-phenol 
• 6482-24-2 2-Bromoethyl methyl ether 
• 627-42-9 2-chloroethyl methyl ether 
• 109-86-4 2-methoxy-ethanol 
• 1266673-99-7 p-bromophenoxyethanol 
• 629-36-7 bis(3-chloropropyl)ether 
• 623-05-2 (4-hydroxyphenyl)methanol 
• 51980-60-0 (4-(2-methoxyethoxy)phenol) 

Downstream Products

• 515160-72-2 1-(4-(2-methoxyethoxy)phenyl)piperazine 
• 377730-05-7 4-hydroxy-4-[4-(2-methoxy-ethoxy)-phenyl]-piperidine-1-carboxylic acid benzyl ester 
• 622386-70-3 tert-butyl 4-({4-[4-(2-methoxyethoxy)phenyl]piperazinyl}sulfonyl)perhydro-2H-pyran-4-carboxylate 
• 377727-87-2 preladenant 
• 377730-06-8 4-(4-(2-methoxyethoxy)phenyl)piperidine 
• 377729-98-1 4-[4-(2-methoxy-ethoxy)-phenyl]-piperidine-1-carboxylic acid benzyl ester 
• 265664-52-6 {4-[2-(methoxy)ethoxy]phenyl}boronic acid 
• 1070716-44-7 4-(5,5-dimethyl-1,3-dioxan-2-yl)-2-[4-(2-methoxyethoxy)phenyl]butanal 
• 1194285-75-0 4-(2-methoxyethoxy)-1-[(tri-n-butyl)stannyl]benzene 
• 1110653-21-8 1-ethynyl-4-(2-methoxyethoxy)benzene 
• 1357170-93-4 5-((4-(2-methoxyethoxy)phenyl)ethynyl)-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one 
• 1357170-99-0 5-(4-(2-methoxyethoxy)phenethyl)-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one 
• 1357171-08-4 2-hydroxy-6-(4-(2-methoxyethoxy)phenethyl)benzoic acid 

Relevant articles and documents

Discovery and mechanism of action studies of 4,6-diphenylpyrimidine-2-carbohydrazides as utrophin modulators for the treatment of Duchenne muscular dystrophy

Duchenne muscular dystrophy is a fatal disease with no cure, caused by lack of the cytoskeletal protein dystrophin. Upregulation of utrophin, a dystrophin paralogue, offers a potential therapy independent of mutation type. The failure of first-in-class utrophin modulator ezutromid/SMT C1100 in Phase II clinical trials necessitates development of compounds with better efficacy, physicochemical and ADME properties and/or complementary mechanisms. We have discovered and performed a preliminary optimisation of a novel class of utrophin modulators using an improved phenotypic screen, where reporter expression is derived from the full genomic context of the utrophin promoter. We further demonstrate through target deconvolution studies, including expression analysis and chemical proteomics, that this compound series operates via a novel mechanism of action, distinct from that of ezutromid.

Pyridine salt / 1,4-dihydropyridine derivative and preparation method thereof

The present invention discloses a pyridine salt / 1,4-dihydropyridine derivative (NAD / NADH analog) with novel structure. The NAD / NADH analog can substitute natural NAD / NADH to be applied to a biochemical system for redox reactions, and can also be used as an electron carrier for the energy transfer of an enzymatic fuel cell. Further, the NAD / NADH analogs provided by the invention are easy to prepare, isolate and purify, and have a high yield.

COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR

Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.