392725-14-3

Basic information

• Product Name: (4R,5R)-4-((3S,4R,5R)-4,5-Dihydroxy-3-methyl-5-phenyl-pentyloxy)-5-isobutoxy-azepane-1-carboxylic acid 3-chloro-4-methoxy-benzylamide
• Synonyms: (4R,5R)-4-((3S,4R,5R)-4,5-Dihydroxy-3-methyl-5-phenyl-pentyloxy)-5-isobutoxy-azepane-1-carboxylic acid 3-chloro-4-methoxy-benzylamide
• CAS NO: 392725-14-3
• Molecular Weight: 577.161
• Mol File: 392725-14-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4R,5R)-4-((3S,4R,5R)-4,5-Dihydroxy-3-methyl-5-phenyl-pentyloxy)-5-isobutoxy-azepane-1-carboxylic acid 3-chloro-4-methoxy-benzylamide(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5R)-4-((3S,4R,5R)-4,5-Dihydroxy-3-methyl-5-phenyl-pentyloxy)-5-isobutoxy-azepane-1-carboxylic acid 3-chloro-4-methoxy-benzylamide(392725-14-3)
• EPA Substance Registry System: (4R,5R)-4-((3S,4R,5R)-4,5-Dihydroxy-3-methyl-5-phenyl-pentyloxy)-5-isobutoxy-azepane-1-carboxylic acid 3-chloro-4-methoxy-benzylamide(392725-14-3)

Safety Data

• Hazardous Substances Data: 392725-14-3(Hazardous Substances Data)

Upstream product

• 392725-08-5 (1R,2R,3S)-4-(tert-Butyl-diphenyl-silanyloxy)-3-methyl-1-phenyl-butane-1,2-diol 
• 392725-09-6 tert-Butyl-[(S)-2-((4R,5R)-2,2-dimethyl-5-phenyl-[1,3]dioxolan-4-yl)-propoxy]-diphenyl-silane 
• 392724-87-7 di-but-3-enyl-carbamic acid 2-trimethylsilanyl-ethyl ester 
• 392724-97-9 2,3,6,7-tetrahydro-azepine-1-carboxylic acid 2-trimethylsilanyl-ethyl ester 
• 392725-12-1 (S)-3-((4R,5R)-2,2-Dimethyl-5-phenyl-[1,3]dioxolan-4-yl)-butyronitrile 
• 392725-13-2 (S)-3-((4R,5R)-2,2-Dimethyl-5-phenyl-[1,3]dioxolan-4-yl)-butan-1-ol 
• 392725-11-0 (4R,5R)-4-((R)-2-Iodo-1-methyl-ethyl)-2,2-dimethyl-5-phenyl-[1,3]dioxolane 
• 392725-10-9 (S)-2-((4R,5R)-2,2-Dimethyl-5-phenyl-[1,3]dioxolan-4-yl)-propan-1-ol 
• 392724-94-6 (4R,5R)-4-((S)-3-Iodo-1-methyl-propyl)-2,2-dimethyl-5-phenyl-[1,3]dioxolane 
• 41965-95-1 (3-chloro-4-methoxyphenyl)methylamine hydrogen chloride 
• 2393-23-9 4-methoxy-benzylamine 
• 1100-88-5 benzyltriphenylphosphonium chloride 
• 132365-02-7 N-benzyl-N-(but-3-enyl)-but-3-en-1-amine 
• 392725-07-4 (R,E)-tert-butyl(2-methyl-4-phenylbut-3-enyloxy)diphenylsilane 

Relevant articles and documents

First generation design, synthesis, and evaluation of azepine-based cryptophycin analogues.

[structure: see text] Azepine-based cryptophycin mimics (+)-4 and (+)-5 have been designed and synthesized. Biological evaluation revealed modest in vitro activity against several human tumor cell lines, thereby supporting the utility of novel scaffolds for the design and synthesis of cryptophycin analogues.