394248-90-9

Basic information

• Product Name: 3-METHOXY-4-(2-PYRROLIDIN-1-YL-ETHOXY)-PHENYLAMINE
• Synonyms: 3-METHOXY-4-(2-PYRROLIDIN-1-YL-ETHOXY)-PHENYLAMINE;3-Methoxy-4-[2-(1-pyrrolidinyl)ethoxy]aniline;3-Methoxy-4-[2-(pyrrolidin-1-yl)ethoxy]aniline
• CAS NO: 394248-90-9
• Molecular Formula: C₁₃H₂₀N₂O₂
• Molecular Weight: 236.3101
• Mol File: 394248-90-9.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 389.145°C at 760 mmHg
• Flash Point: 189.148°C
• Appearance: /
• Density: 1.115g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.559
• CAS DataBase Reference: 3-METHOXY-4-(2-PYRROLIDIN-1-YL-ETHOXY)-PHENYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHOXY-4-(2-PYRROLIDIN-1-YL-ETHOXY)-PHENYLAMINE(394248-90-9)
• EPA Substance Registry System: 3-METHOXY-4-(2-PYRROLIDIN-1-YL-ETHOXY)-PHENYLAMINE(394248-90-9)

Safety Data

• Hazardous Substances Data: 394248-90-9(Hazardous Substances Data)

Usage

General Description

3-METHOXY-4-(2-PYRROLIDIN-1-YL-ETHOXY)-PHENYLAMINE, also known as MPPE, is a chemical compound with potential pharmaceutical applications. It is a derivative of phenethylamine and is structurally similar to the neurotransmitter serotonin. MPPE has been studied for its potential as a medication for various psychiatric and neurological disorders, including depression, anxiety, and schizophrenia. It acts as a selective serotonin and norepinephrine reuptake inhibitor, which could make it useful in treating mood disorders. However, further research is needed to fully understand the pharmacological properties and potential therapeutic uses of this compound.

InChI:InChI=1/C13H20N2O2/c1-16-13-10-11(14)4-5-12(13)17-9-8-15-6-2-3-7-15/h4-5,10H,2-3,6-9,14H2,1H3

Upstream product

• 2287-10-7 1-[2-(2-methoxy-4-nitrophenoxy)ethyl]pyrrolidine 
• 3251-56-7 2-methoxy-4-nitrophenol 
• 7250-67-1 1-(2-chloroethyl)pyrrolidine hydrochloride 
• 100200-99-5 potassium 2-methoxy-4-nitrophenolate monohydrate 
• 2955-88-6 1-pyrrolidineethanol 
• 454-16-0 1-fluoro-2-methoxy-4-nitrobenzene 

Downstream Products

• 515141-48-7 5-bromo-3-nitro-thiophene-2-carboxylic acid [3-methoxy-4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amide 
• 515879-16-0 2-amino-5-phenyl-thiophene-3-carboxylic acid [3-methoxy-4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amide 
• 515878-89-4 3-nitro-biphenyl-4-carboxylic acid [3-methoxy-4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amide 
• 515879-21-7 3-{3-[3-methoxy-4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-thioureido}-5-phenyl-thiophene-2-carboxylic acid methyl ester 
• 515878-82-7 N-[3-methoxy-4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-2-nitro-4-phenoxy-benzamide 
• 515879-13-7 4'-chloro-4-nitro-biphenyl-3-carboxylic acid [3-methoxy-4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amide 

Relevant articles and documents

ISOQUINOLINONE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER

The present invention relates to a compound of the following formula (I) or a pharmaceutically acceptable salt and/or solvate thereof, notably for use as a drug, notably in the treatment of cancer, as well as pharmaceutical compositions containing such a

NOVEL AMINOALCOHOL-SUBSTITUTED ARYLDIHYDROISOQUINOLINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS

The invention relates to aminoalcohol-substituted aryldihydroisoquinolinones and their derivatives, and their physiologically tolerated salts and physiologically functional derivatives, their preparation, medicaments comprising at least one aminoalcohol-substituted aryldihydroisoquinolinone of the invention or its derivative, and the use of the aminoalcohol- substituted aryldihydroisoquinolinones of the invention and their derivatives as MCH antagonists.

NOVEL MCH RECEPTOR ANTAGONISTS

The present invention relates to a melanin concentrating hormone antagonist compound of formula (I): wherein R1, Ra, Rb, R2, L1, R3, R4 and R5 are as defined, or a pharmaceutically acceptable salt, enantiomer, diastereomer or mixture of diasteromers thereof useful in the treatment, obesity and related diseases.